Scientific article

Titanium nitride oxide coating on rough titanium stimulates the proliferation of human primary osteoblasts

Published inClinical oral implants research, vol. 22, no. 5, p. 552-559
Publication date2011

Titanium is widely used in contemporary endosseous implantology and there is considerable thrust to further promote osseointegration by implant surface modifications. The aim of this study was to evaluate the effect of a titanium-nitride-oxide (TiNOx) coating on commercially pure microroughened titanium by assessing the proliferation and differentiation of human primary osteoblasts.

  • Acid Etching, Dental/methods
  • Alkaline Phosphatase/analysis
  • Alloys/chemistry
  • Aluminum Oxide/chemistry
  • Calcitriol/pharmacology
  • Calcium Channel Agonists/pharmacology
  • Cell Adhesion/physiology
  • Cell Count
  • Cell Differentiation/drug effects/physiology
  • Cell Proliferation/drug effects
  • Cells, Cultured
  • Coated Materials, Biocompatible/chemistry
  • Dental Etching/methods
  • Dental Materials/chemistry
  • Gene Expression Regulation
  • Humans
  • Hydrochloric Acid/chemistry
  • Microscopy, Electron, Scanning
  • Osteoblasts/drug effects/physiology
  • Osteocalcin/analysis
  • Osteoprotegerin/analysis
  • Photoelectron Spectroscopy
  • Plasma Gases/chemistry
  • Reverse Transcriptase Polymerase Chain Reaction
  • Surface Properties
  • Titanium/chemistry
Citation (ISO format)
DURUAL, Stéphane et al. Titanium nitride oxide coating on rough titanium stimulates the proliferation of human primary osteoblasts. In: Clinical oral implants research, 2011, vol. 22, n° 5, p. 552–559. doi: 10.1111/j.1600-0501.2010.02033.x
Main files (1)
Article (Published version)
ISSN of the journal0905-7161

Technical informations

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