The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques
ContributorsMontecucco, Fabrizio; Di Marzo, Vincenzo; da Silva, Rafaela F; Vuilleumier, Nicolas; Capettini, Luciano; Lenglet, Sébastien; Pagano, Sabrina
Published inEuropean heart journal, vol. 33, no. 7, p. 846-856
Publication date2012
Abstract
Keywords
- Aged
- Animals
- Aorta, Thoracic/metabolism
- Cannabinoids/pharmacology
- Carotid Artery, Internal/metabolism
- Carotid Stenosis/metabolism
- Case-Control Studies
- Female
- Flavonoids/pharmacology
- Humans
- Indoles/pharmacology
- MAP Kinase Signaling System/physiology
- Male
- Matrix Metalloproteinase 9/metabolism/physiology
- Mice
- Mice, Inbred C57BL
- Neutrophils/metabolism
- Phosphorylation/physiology
- Plaque, Atherosclerotic/metabolism
- Protein Kinase Inhibitors/pharmacology
- Receptor, Cannabinoid, CB2/antagonists & inhibitors/metabolism
- Tumor Necrosis Factor-alpha/metabolism
Affiliation
- Faculté de médecine / Section de médecine fondamentale / Département de biologie structurale et bioinformatique
- Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie
- Faculté de médecine / Section de médecine clinique / Département de médecine
- Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires
Citation (ISO format)
MONTECUCCO, Fabrizio et al. The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques. In: European heart journal, 2012, vol. 33, n° 7, p. 846–856. doi: 10.1093/eurheartj/ehr449
Main files (1)
Article (Published version)
Identifiers
- PID : unige:27585
- DOI : 10.1093/eurheartj/ehr449
- PMID : 22112961
ISSN of the journal0195-668X
