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EasyProt - An easy-to-use graphical platform for proteomics data analysis

Fétaud, Vanessa
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Published in Journal of proteomics. 2013, vol. 79, p. 146-60
Abstract High throughput protein identification and quantification analysis based on mass spectrometry are fundamental steps in most proteomics projects. Here, we present EasyProt (available at http://easyprot.unige.ch), a new platform for mass spectrometry data processing, protein identification, quantification and unexpected post-translational modification characterization. EasyProt provides a fully integrated graphical experience to perform a large part of the proteomic data analysis workflow. Our goal was to develop a software platform that would fulfill the needs of scientists in the field, while emphasizing ease-of-use for non-bioinformatician users. Protein identification is based on OLAV scoring schemes and protein quantification is implemented for both, isobaric labeling and label-free methods. Additional features are available, such as peak list processing, isotopic correction, spectra filtering, charge-state deconvolution and spectra merging. To illustrate the EasyProt platform, we present two identification and quantification workflows based on isobaric tagging and label-free methods.
Keywords Protein identificationProtein quantificationLabel-freeIsobaric labelingPost-translational modificationsMass spectrometry
PMID: 23277275
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Research groups Chimie et protéomique clinique (270)
Groupe de Protéomique biomédicale (635)
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GLUCK, Florent et al. EasyProt - An easy-to-use graphical platform for proteomics data analysis. In: Journal of proteomics, 2013, vol. 79, p. 146-60. doi: 10.1016/j.jprot.2012.12.012 https://archive-ouverte.unige.ch/unige:26872

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Deposited on : 2013-03-19

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