Scientific article
OA Policy
English

Increased expression of adenosine triphosphate-sensitive K+ channels in mitral dysfunction: mechanically stimulated transcription and hypoxia-induced protein stability?

Published inJournal of the American College of Cardiology, vol. 59, no. 4, p. 390-396
Publication date2012
Abstract

The aim of this study was to test whether adenosine triphosphate-sensitive K(+) (KATP) channel expression relates to mechanical and hypoxic stress within the left human heart.

Keywords
  • Aged
  • Animals
  • Anoxia/metabolism
  • Blood Gas Analysis
  • Blood Pressure
  • Echocardiography
  • Female
  • Gene Expression Regulation
  • Heart Ventricles/metabolism
  • Humans
  • Hypoxia-Inducible Factor 1
  • Alpha Subunit/metabolism
  • KATP Channels/metabolism
  • Male
  • Mice
  • Knockout
  • Middle Aged
  • Mitral Valve Insufficiency/metabolism
  • Myocardium/metabolism
  • Oxygen/physiology
  • Partial Pressure
  • Potassium Channels
  • Inwardly Rectifying/metabolism
  • Protein Stability
  • RNA
  • Messenger/metabolism
  • Stress
  • Mechanical
Citation (ISO format)
RAEIS, Véronique et al. Increased expression of adenosine triphosphate-sensitive K+ channels in mitral dysfunction: mechanically stimulated transcription and hypoxia-induced protein stability? In: Journal of the American College of Cardiology, 2012, vol. 59, n° 4, p. 390–396. doi: 10.1016/j.jacc.2011.08.077
Main files (1)
Article (Published version)
accessLevelPublic
Identifiers
Journal ISSN0735-1097
597views
298downloads

Technical informations

Creation08/11/2012 17:53:00
First validation08/11/2012 17:53:00
Update time14/03/2023 21:01:58
Status update14/03/2023 21:01:58
Last indexation30/10/2024 09:46:15
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack