Increased expression of adenosine triphosphate-sensitive K+ channels in mitral dysfunction: mechanically stimulated transcription and hypoxia-induced protein stability?

Article Article scientifique Article Increased expression of adenosine triphosphate-sensitive K+ channels in mitral dysfunction: mechanically stimulated transcription and hypoxia-induced protein stability? eng 2012 author Raeis Véronique 637180 author Philip-Couderc Pierre 590338 author Faggian Giuseppe author Tessari Maddalena author Baertschi Angela 23608 author Milano Aldo D author Bochaton-Piallat Marie-Luce 23951 Marie-Luce Piallat author Baertschi Alex 110207 390-396 10.1016/j.jacc.2011.08.077 22133355 0735-1097 The aim of this study was to test whether adenosine triphosphate-sensitive K(+) (KATP) channel expression relates to mechanical and hypoxic stress within the left human heart. Aged Animals Anoxia/metabolism Blood Gas Analysis Blood Pressure Echocardiography Female Gene Expression Regulation Heart Ventricles/metabolism Humans Hypoxia-Inducible Factor 1 Alpha Subunit/metabolism KATP Channels/metabolism Male Mice Knockout Middle Aged Mitral Valve Insufficiency/metabolism Myocardium/metabolism Oxygen/physiology Partial Pressure Potassium Channels Inwardly Rectifying/metabolism Protein Stability RNA Messenger/metabolism Stress Mechanical Dewey 616.07 Dewey 616.8 Dewey 618.92 53 Département de neurosciences fondamentales 21A 137 Département de pathologie et immunologie 21F false 380 Bochaton-Piallat Marie-Luce (pathologie et immunologie) 646 Journal of the American College of Cardiology 59 4 19cbfb73-1378-4fb4-b367-1a6bf97a70af Article (Published version) Public Raeis-Dauve-JACC _2011.pdf 887453 application/pdf openAccess Faculté de médecine / Section de médecine fondamentale / Département de neurosciences fondamentales Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie

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Increased expression of adenosine triphosphate-sensitive K+ channels in mitral dysfunction: mechanically stimulated transcription and hypoxia-induced protein stability?	Journal of the American College of Cardiology			2012	588	295

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Baertschi, Angela