Dominant-negative tumor necrosis factor protects from Mycobacterium bovis Bacillus Calmette-Guérin (BCG) and endotoxin-induced liver injury without compromising host immunity to BCG and Mycobacterium tuberculosis
Published inThe Journal of infectious diseases, vol. 199, no. 7, p. 1053-1063
Publication date2009
Abstract
Keywords
- Animals
- Cell Line
- Drug-Induced Liver Injury
- Immunoglobulin G/pharmacology
- Immunosuppressive Agents/pharmacology
- Lipopolysaccharides/toxicity
- Liver Diseases/prevention & control
- Lung/pathology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mycobacterium bovis/immunology
- Mycobacterium tuberculosis/immunology
- Receptors, Tumor Necrosis Factor
- Tuberculosis/immunology/pathology
- Tumor Necrosis Factor-alpha/antagonists & inhibitors/pharmacology/physiology
Funding
- Swiss National Science Foundation - 3200A0-118196
- Autre - TB REACT
Citation (ISO format)
OLLEROS, Maria-Luisa et al. Dominant-negative tumor necrosis factor protects from Mycobacterium bovis Bacillus Calmette-Guérin (BCG) and endotoxin-induced liver injury without compromising host immunity to BCG and Mycobacterium tuberculosis. In: The Journal of infectious diseases, 2009, vol. 199, n° 7, p. 1053–1063. doi: 10.1086/597204
Main files (1)
Article (Published version)

Identifiers
- PID : unige:25862
- DOI : 10.1086/597204
- PMID : 19222369
ISSN of the journal0022-1899