Aurora A in cell division: kinase activity not required

Kress, Elsa; Gotta, Monica

doi:10.1038/ncb2276

Scientific article

Comment

English

Aurora A in cell division: kinase activity not required

ContributorsKress, Elsa; Gotta, Monica

Published inNature cell biology, vol. 13, no. 6, p. 638-639

Publication date2011

Abstract

Aurora A kinase is a key regulator of cell division, whose functions were attributed to its ability to phosphorylate diverse substrates. Aurora A is now shown to have a kinase-independent role in the regulation of chromatin-mediated microtubule assembly.

Keywords

Animals
Caenorhabditis elegans/enzymology
Cell Division/physiology
Microtubules/metabolism
Phosphorylation
Protein-Serine-Threonine Kinases/chemistry/metabolism

Affiliation entities

Faculté de médecine / Section de médecine fondamentale / Département de physiologie cellulaire et métabolisme

Research groups

La division asymétrique (847)

Citation (ISO format)

KRESS, Elsa, GOTTA, Monica. Aurora A in cell division: kinase activity not required. In: Nature cell biology, 2011, vol. 13, n° 6, p. 638–639. doi: 10.1038/ncb2276

Article (Published version)

Identifiers

PID : unige:25588
DOI : 10.1038/ncb2276
PMID : 21572422

Journal ISSN1465-7392

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Creation11/13/2012 10:14:00 AM

First validation11/13/2012 10:14:00 AM

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Aurora A in cell division: kinase activity not required

Aurora A kinase is a key regulator of cell division, whose functions were attributed to its ability to phosphorylate diverse substrates. Aurora A is now shown to have a kinase-independent role in the regulation of chromatin-mediated microtubule assembly.

Technical informations