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Title

IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C.

Authors
Haagmans, B
Ferrari, C
Missale, G
Zeuzem, S
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Published in Journal of Hepatology. 2011, vol. 55, no. 5, p. 980-8
Abstract Single nucleotide polymorphisms (SNPs) associated with IL28B influence the outcome of peginterferon-α/ribavirin therapy of chronic hepatitis C virus (HCV) infection. We analyzed the kinetics of HCV RNA during therapy as a function of IL28B SNPs.
Keywords AdultAllelesAntiviral Agents/therapeutic useFemaleGene FrequencyGenotypeHepacivirus/genetics/physiologyHepatitis C, Chronic/drug therapy/geneticsHumansInterferon-alpha/therapeutic useInterleukins/geneticsMaleMiddle AgedMultivariate AnalysisPolyethylene Glycols/therapeutic usePolymorphism, Single Nucleotide/geneticsRNA, Viral/bloodRecombinant Proteins/therapeutic useRibavirin/therapeutic useTime Factors
Identifiers
PMID: 21354446
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Structures
Research group Etudes et traitement de l'hépatite C et B (554)
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BOCHUD, Pierre-Yves et al. IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C. In: Journal of Hepatology, 2011, vol. 55, n° 5, p. 980-8. https://archive-ouverte.unige.ch/unige:25376

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Deposited on : 2013-01-11

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