IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C

Article Article scientifique Article IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C eng 2011 author Bochud Pierre-Yves 690825 author Bibert Stéphanie 693550 author Negro Francesco 96509 author Haagmans B author Soulier Anthony André 632150 author Ferrari C author Missale G author Zeuzem S author Pawlotsky J-M author Schalm S author Hellstrand K author Neumann A U author Lagging M 980-988 10.1016/j.jhep.2011.01.050 21354446 0168-8278 Single nucleotide polymorphisms (SNPs) associated with IL28B influence the outcome of peginterferon-α/ribavirin therapy of chronic hepatitis C virus (HCV) infection. We analyzed the kinetics of HCV RNA during therapy as a function of IL28B SNPs. Adult Alleles Antiviral Agents/therapeutic use Female Gene Frequency Genotype Hepacivirus/genetics/physiology Hepatitis C, Chronic/drug therapy/genetics Humans Interferon-alpha/therapeutic use Interleukins/genetics Male Middle Aged Multivariate Analysis Polyethylene Glycols/therapeutic use Polymorphism, Single Nucleotide/genetics RNA, Viral/blood Recombinant Proteins/therapeutic use Ribavirin/therapeutic use Time Factors Dewey 616 Dewey 616.07 137 Département de pathologie et immunologie 21F 56 Département de médecine 221 false 297 Etudes et traitement de l'hépatite C et B 554 Journal of hepatology 55 5 f9e1aee6-8868-4c06-9369-f8f482a426d7 Article (Published version) Restricted Negro F J Hepatol2011, 55(5), 980.pdf 928022 application/pdf restrictedAccess Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie Faculté de médecine / Section de médecine clinique / Département de médecine

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IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C	Journal of hepatology			2011	616	0

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Soulier, Anthony André