Scientific article
English

Combined analysis of grey matter voxel-based morphometry and white matter tract-based spatial statistics in late-life bipolar disorder

Published inJournal of psychiatry & neuroscience, vol. 36, no. 6, p. 391-401
Publication date2011
Abstract

Previous magnetic resonance imaging (MRI) studies in young patients with bipolar disorder indicated the presence of grey matter concentration changes as well as microstructural alterations in white matter in various neocortical areas and the corpus callosum. Whether these structural changes are also present in elderly patients with bipolar disorder with long-lasting clinical evolution remains unclear.

Keywords
  • Aged
  • Anisotropy
  • Bipolar Disorder/pathology/psychology
  • Brain/pathology
  • Case-Control Studies
  • Diffusion Tensor Imaging/methods/psychology/statistics & numerical data
  • Female
  • Humans
  • Male
  • Nerve Fibers, Myelinated/pathology
  • Nerve Fibers, Unmyelinated/pathology
  • Neuroimaging/methods/psychology/statistics & numerical data
  • Neuropsychological Tests/statistics & numerical data
Citation (ISO format)
HALLER, Sven et al. Combined analysis of grey matter voxel-based morphometry and white matter tract-based spatial statistics in late-life bipolar disorder. In: Journal of psychiatry & neuroscience, 2011, vol. 36, n° 6, p. 391–401. doi: 10.1503/jpn.100140
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Additional URL for this publicationhttp://www.cma.ca/jpn/vol-36/issue-6/391
Journal ISSN1180-4882
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