Viral suppression rates in salvage treatment with raltegravir improved with the administration of genotypic partially active or inactive nucleoside/tide reverse transcriptase inhibitors

Scherrer, Alexandra U; von Wyl, Viktor; Böni, Jürg; Yerly Ferrillo, Sabine; Klimkait, Thomas; Bürgisser, Philippe; Garzoni, Christian; Hirschel, Bernard; Cavassini, Matthias; Battegay, Manuel; Vernazza, Pietro L; Bernasconi, Enos; Ledergerber, Bruno; Günthard, Huldrych F

doi:10.1097/QAI.0b013e318211925e

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Title		Viral suppression rates in salvage treatment with raltegravir improved with the administration of genotypic partially active or inactive nucleoside/tide reverse transcriptase inhibitors
Authors		Scherrer, Alexandra U von Wyl, Viktor Böni, Jürg Yerly Ferrillo, Sabine Klimkait, Thomas Bürgisser, Philippe Garzoni, Christian Hirschel, Bernard Cavassini, Matthias Battegay, Manuel Vernazza, Pietro L Bernasconi, Enos Ledergerber, Bruno Günthard, Huldrych F show all authors [1 - 14]
Published in		Journal of Acquired Immune Deficiency Syndromes. 2011, vol. 57, no. 1, p. 24-31
Abstract		Nucleoside reverse transcriptase inhibitors (NRTIs) are often administered in salvage therapy even if genotypic resistance tests (GRTs) indicate high-level resistance, but little is known about the benefit of these additional NRTIs.
Keywords		Adult — Anti-HIV Agents/administration & dosage — Cohort Studies — Female — HIV Infections/blood/drug therapy/virology — HIV-1/growth & development — Humans — Logistic Models — Male — Middle Aged — Proportional Hazards Models — Pyrrolidinones/administration & dosage — RNA, Viral/blood — Reverse Transcriptase Inhibitors/administration & dosage — Salvage Therapy/methods
Identifiers		DOI: 10.1097/QAI.0b013e318211925e PMID: 21283013
Full text		Article (Published version) (130 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine
Research groups		Groupe Laurent Kaiser (virologie clinique) (668) Unité HIV (46)
Citation (ISO format)		SCHERRER, Alexandra U et al. Viral suppression rates in salvage treatment with raltegravir improved with the administration of genotypic partially active or inactive nucleoside/tide reverse transcriptase inhibitors. In: Journal of Acquired Immune Deficiency Syndromes, 2011, vol. 57, n° 1, p. 24-31. doi: 10.1097/QAI.0b013e318211925e https://archive-ouverte.unige.ch/unige:25321