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Title

Viral genotype-specific role of PNPLA3, PPARG, MTTP, and IL28B in hepatitis C virus-associated steatosis

Authors
Cai, Tao
Muellhaupt, Beat
Heim, Markus
Moradpour, Darius
Cerny, Andreas
Malinverni, Raffaele
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Published in Journal of Hepatology. 2011, vol. 55, no. 3, p. 529-35
Abstract Steatosis is a prominent feature of hepatitis C, especially in patients infected with genotype 3. The analysis of genetic polymorphisms influencing steatosis in chronic hepatitis C has been limited by the studies' small sample size, and important single nucleotide polymorphisms (SNPs), such as those in the patatin-like phospholipase family 3 protein (PNPLA3), were never evaluated.
Keywords AdultCarrier Proteins/geneticsFatty Liver/complications/genetics/virologyFemaleGenotypeHepacivirus/geneticsHepatitis C, Chronic/complications/virologyHumansInterleukins/geneticsLipase/geneticsLogistic ModelsMaleMembrane Proteins/geneticsMiddle AgedPPAR gamma/geneticsPolymorphism, Single NucleotideSeverity of Illness Index
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PMID: 21236304
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Article (Published version) (622 Kb) - document accessible for UNIGE members only Limited access to UNIGE
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Research group Etudes et traitement de l'hépatite C et B (554)
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CAI, Tao et al. Viral genotype-specific role of PNPLA3, PPARG, MTTP, and IL28B in hepatitis C virus-associated steatosis. In: Journal of Hepatology, 2011, vol. 55, n° 3, p. 529-35. https://archive-ouverte.unige.ch/unige:25297

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Deposited on : 2013-01-10

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