UNIGE document Scientific Article
previous document  unige:24048  next document
add to browser collection

Haemodynamic responses to temperature changes of human skeletal muscle studied by laser-Doppler flowmetry

Published in Physiological measurement. 2012, vol. 33, no. 7, p. 1181-97
Abstract Using a small, but very instructive experiment, it is demonstrated that laser-Doppler flowmetry (LDF) at large interoptode spacing represents a unique tool for new investigations of thermoregulatory processes modulating the blood flow of small muscle masses in humans. It is shown on five healthy subjects that steady-state values of blood flow (perfusion) in the thenar eminence muscle group depend in a complex manner on both the local intramuscular temperature and local skin temperature, while the values of blood flow parameters measured during physiological transients, such as the post-ischaemic hyperhaemic response, depend only on the intramuscular temperature. In addition, it is shown that the so-called biological zero (i.e. remaining LDF signal during arterial occlusion) is influenced not only as expected by the intramuscular temperature, but also by the skin temperature. The proposed results reveal that the skeletal muscle has unique thermoregulatory characteristics compared, for example, to human skin. These and other observations represent new findings and we hope that they will serve as a stimulus for the creation of new experimental protocols leading to better understanding of blood flow regulation.
PMID: 22735191
Full text
Article (Published version) (1.3 MB) - document accessible for UNIGE members only Limited access to UNIGE
Research groups Groupe Binzoni Tiziano (radiologie) (234)
Traitement d'images médicales (893)
(ISO format)
BINZONI, Tiziano et al. Haemodynamic responses to temperature changes of human skeletal muscle studied by laser-Doppler flowmetry. In: Physiological measurement, 2012, vol. 33, n° 7, p. 1181-97. doi: 10.1088/0967-3334/33/7/1181 https://archive-ouverte.unige.ch/unige:24048

558 hits

1 download


Deposited on : 2012-11-16

Export document
Format :
Citation style :