UNIGE document Scientific Article
previous document  unige:24022  next document
add to browser collection

White-matter connectivity between face-responsive regions in the human brain

Gschwind, Markus A.
Published in Cerebral Cortex. 2012, vol. 22, no. 7, p. 1564-76
Abstract Face recognition is of major social importance and involves highly selective brain regions thought to be organized in a distributed functional network. However, the exact architecture of interconnections between these regions remains unknown. We used functional magnetic resonance imaging to identify face-responsive regions in 22 participants and then employed diffusion tensor imaging with probabilistic tractography to establish the white-matter pathways between these functionally defined regions. We identified strong white-matter connections between the occipital face area (OFA) and fusiform face area (FFA), with a significant right-hemisphere predominance. We found no evidence for direct anatomical connections between FFA and superior temporal sulcus (STS) or between OFA and STS, contrary to predictions based on current cognitive models. Instead, our findings point to segregated processing along a ventral extrastriate visual pathway to OFA-FFA and another more dorsal system connected to STS and frontoparietal areas. In addition, early occipital areas were found to have direct connections to the amygdala, which might underlie a rapid recruitment of limbic brain areas by visual inputs bypassing more elaborate extrastriate cortical processing. These results unveil the structural neural architecture of the human face recognition system and provide new insights on how distributed face-responsive areas may work together.
PMID: 21893680
Full text
Article (Published version) (731 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Research groups Affective sciences
Mécanismes cérébraux du comportement et des fonctions cognitives (701)
Neuroimagerie du Sommeil et de la Cognition (832)
Traitement d'images médicales (893)
(ISO format)
GSCHWIND, Markus A. et al. White-matter connectivity between face-responsive regions in the human brain. In: Cerebral Cortex, 2012, vol. 22, n° 7, p. 1564-76. doi: 10.1093/cercor/bhr226 https://archive-ouverte.unige.ch/unige:24022

499 hits



Deposited on : 2012-11-14

Export document
Format :
Citation style :