Longitudinal analysis of cognitive performances and structural brain changes in late-life bipolar disorder

Delaloye, Christophe; Moy, Guenael; De Bilbao, Fabienne; Weber, Kerstin Maud; Baudois, S.; Haller, Sven; Xekardaki, Aikaterini; Canuto, Alessandra; Giardini, U.; Lövblad, Karl-Olof; Gold, Gabriel; Giannakopoulos, Panteleimon

doi:10.1002/gps.2683

Scientific article

English

Longitudinal analysis of cognitive performances and structural brain changes in late-life bipolar disorder

ContributorsDelaloye, Christophe; Moy, Guenael; De Bilbao, Fabienne; Weber, Kerstin Maud; Baudois, S.; Haller, Sven; Xekardaki, Aikaterini; Canuto, Alessandra; Giardini, U.; Lövblad, Karl-Olof; Gold, Gabriel; Giannakopoulos, Panteleimon

Published inInternational journal of geriatric psychiatry, vol. 26, no. 12, p. 1309-1318

Publication date2011

Abstract

Cross-sectional studies in bipolar disorder (BD) suggested the presence of cognitive deficits and subtle magnetic resonance imaging (MRI) changes in limbic areas that may persist at euthymic stages. Whether or not cognitive and MRI changes represent stable attributes of BD or evolve with time is still matter of debate. To address this issue, we performed a 2-year longitudinal study including detailed neuropsychological and magnetic resonance imaging (MRI) analyses of 15 euthymic older BD patients and 15 controls.

Keywords

Aged
Analysis of Variance
Bipolar Disorder/pathology/psychology
Brain/pathology
Cognition Disorders/etiology/pathology
Executive Function/physiology
Female
Humans
Longitudinal Studies
Magnetic Resonance Imaging
Male
Middle Aged
Neuropsychological Tests

Affiliation

Research group

Groupe Giannakopoulos Panteleimon (psychiatrie générale) (201)

Citation (ISO format)

DELALOYE, Christophe et al. Longitudinal analysis of cognitive performances and structural brain changes in late-life bipolar disorder. In: International journal of geriatric psychiatry, 2011, vol. 26, n° 12, p. 1309–1318. doi: 10.1002/gps.2683

Article (Published version)

Identifiers

PID : unige:23973
DOI : 10.1002/gps.2683
PMID : 21394788

ISSN of the journal0885-6230

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Longitudinal analysis of cognitive performances and structural brain changes in late-life bipolar disorder

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