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Comment on "Ongoing Adaptive Evolution of ASPM, a Brain Size Determinant in Homo sapiens" and "Microcephalin, a Gene Regulating Brain Size, Continues to Evolve Adaptively in Humans"

Authors
Maddison, Wayne
Otto, Sarah P.
Whitlock, Michael C.
Yeaman, Sam
Published in Science. 2006, vol. 313, no. 5784, p. 172
Abstract Mekel-Bobrov et al. and Evans et al. (Reports, 9 Sept. 2005, p. 1720 and p. 1717, respectively) examined sequence data from modern humans within two gene regions associated with brain development, ASPM and microcephalin, and concluded that selection of these genes must be ongoing. We show that models of human history that include both population growth and spatial structure can generate the observed patterns without selection.
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Research group Unité d’anthropologie
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CURRAT, Mathias et al. Comment on "Ongoing Adaptive Evolution of ASPM, a Brain Size Determinant in Homo sapiens" and "Microcephalin, a Gene Regulating Brain Size, Continues to Evolve Adaptively in Humans". In: Science, 2006, vol. 313, n° 5784, p. 172. https://archive-ouverte.unige.ch/unige:2122

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Deposited on : 2009-06-22

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