UNIGE document Scientific Article
previous document  unige:21000  next document
add to browser collection

Frequency and determinants of unprotected sex among HIV-infected persons: the Swiss HIV cohort study

Hasse, Barbara
Ledergerber, Bruno
Vernazza, Pietro
Glass, Tracy R.
Jeannin, Andre
Evison, John-Marc
Elzi, Luigia
show hidden authors show all authors [1 - 12]
Published in Clinical infectious diseases. 2010, vol. 51, no. 11, p. 1314-1322
Abstract BACKGROUND: Access to antiretroviral therapy may have changed condom use behavior. In January 2008, recommendations on condom use for human immunodeficiency virus (HIV)-positive persons were published in Switzerland, which allowed for unprotected sex under well-defined circumstances ("Swiss statement"). We studied the frequency, changes over time, and determinants of unprotected sex among HIV-positive persons. METHODS: Self-reported information on sexual preference, sexual partners, and condom use was collected at semi-annual visits in all participants of the prospective Swiss HIV Cohort Study from April 2007 through March 2009. Multivariable logistic regression models were fit using generalized estimating equations to investigate associations between characteristics of cohort participants and condom use. FINDINGS: A total of 7309 participants contributed to 21,978 visits. A total of 4291 persons (80%) reported sexual contacts with stable partners, 1646 (30%) with occasional partners, and 557 (10%) with stable and occasional partners. Of the study participants, 5838 (79.9%) of 7309 were receiving antiretroviral therapy, and of these, 4816 patients (82%) had a suppressed viral load. Condom use varied widely and differed by type of partner (visits with stable partners, 10,368 [80%] of 12,983; visits with occasional partners, 4300 [88%] of 4880) and by serostatus of stable partner (visits with HIV-negative partners, 7105 [89%] of 8174; visits with HIV-positive partners, 1453 [48%] of 2999). Participants were more likely to report unprotected sex with stable partners if they were receiving antiretroviral therapy, if HIV replication was suppressed, and after the publication of the "Swiss statement." Noninjection drug use and moderate or severe alcohol use were associated with unprotected sex. CONCLUSIONS: Antiretroviral treatment and plasma HIV RNA titers influence sexual behavior of HIV-positive persons. Noninjection illicit drug and alcohol use are important risk factors for unprotected sexual contacts.
Keywords AdolescentAdultAgedAlcoholism/psychologyAnti-HIV Agents/therapeutic useCohort StudiesFemaleHIV Infections/*drug therapy/*psychology/transmission/virologyHumansMaleMiddle AgedProspective StudiesRisk FactorsSubstance-Related Disorders/psychologySwitzerlandUnsafe Sex/*psychology/*statistics & numerical dataViral LoadYoung Adult
PMID: 21034200
Full text
Article - document accessible for UNIGE members only Limited access to UNIGE
Other version: http://cid.oxfordjournals.org/content/51/11/1314.full.pdf
Research group Unité HIV (46)
(ISO format)
HASSE, Barbara et al. Frequency and determinants of unprotected sex among HIV-infected persons: the Swiss HIV cohort study. In: Clinical infectious diseases, 2010, vol. 51, n° 11, p. 1314-1322. doi: 10.1086/656809 https://archive-ouverte.unige.ch/unige:21000

510 hits

0 download


Deposited on : 2012-05-23

Export document
Format :
Citation style :