

Other version: http://jid.oxfordjournals.org/content/202/10/1482.full.pdf
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Failure to detect xenotropic murine leukemia virus-related virus in blood of individuals at high risk of blood-borne viral infections |
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Published in | The journal of infectious diseases. 2010, vol. 202, no. 10, p. 1482-1485 | |
Abstract | A xenotropic murine leukemia virus-related virus (XMRV) has recently been reported in association with prostate cancer and chronic fatigue syndrome, with a prevalence of up to 3.7% in the healthy population. We looked for XMRV in 230 patients with human immunodeficiency virus type 1 or hepatitis C infection. XMRV was undetectable in plasma or peripheral blood mononuclear cells by polymerase chain reaction targeting XMRV gag or env. T cell responses to XMRV Gag were undetectable in peripheral blood mononuclear cells by ex vivo gamma interferon enzyme-linked immunospot assay. In our cohorts, XMRV was not enriched in patients with blood-borne or sexually transmitted infections from the United Kingdom and Western Europe. | |
Keywords | Adult — Aged — Cohort Studies — Enzyme-Linked Immunosorbent Assay — Europe/epidemiology — Female — Gene Products, gag/genetics/immunology — Genes, Viral/genetics — Great Britain/epidemiology — HIV Infections/blood/*virology — *Hiv-1 — Hepatitis C, Chronic/blood/*virology — Humans — Interferon-gamma/blood — Leukemia Virus, Murine/genetics/*isolation & purification — Leukocytes, Mononuclear/virology — Male — Middle Aged — Polymerase Chain Reaction — Retroviridae Infections/blood/*epidemiology/virology — Risk Factors — Tumor Virus Infections/blood/*epidemiology/virology — Viral Envelope Proteins/genetics — Young Adult | |
Identifiers | DOI: 10.1086/657167 PMID: 20936982 | |
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![]() ![]() Other version: http://jid.oxfordjournals.org/content/202/10/1482.full.pdf |
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Research group | Unité HIV (46) | |
Citation (ISO format) | BARNES, Eleanor et al. Failure to detect xenotropic murine leukemia virus-related virus in blood of individuals at high risk of blood-borne viral infections. In: The Journal of infectious diseases, 2010, vol. 202, n° 10, p. 1482-1485. doi: 10.1086/657167 https://archive-ouverte.unige.ch/unige:20760 |