Different types of lipid molecule are transported around the cell by lipid-transfer proteins. Biochemical approaches have been adapted to measure which lipids are captured by the more than 130 known human lipid-transfer proteins, providing a valuable resource that reveals some principles of how these transporters work.

Summary of : Titeca K, Chiapparino A, Hennrich ML, Türei D, Moqadam M, Talandashti R, Cuveillier C, van Ek L, Zukowska J, Triana S, Echelard F, Nielsen IØ, Foged MM, Gehin C, Olechnovic K, Grudinin S, Saez-Rodriguez J, Alexandrov T, Maeda K, Reuter N, Gavin AC. Systematic analyses of lipid mobilization by human lipid transfer proteins. Nature. 2026 Mar;651(8105):511-520. doi: 10.1038/s41586-025-10040-y. Epub 2026 Jan 7. PMID: 41501472; PMCID: PMC12979188. https://archive-ouverte.unige.ch/unige:190424