Scientific article
Open access

Unconventional myosins at the crossroad of signal transduction and cytoskeleton remodeling

Published inProtoplasma, vol. 209, no. 1-2, p. 28-37
Publication date1999

The cytoplasm of eukaryotic cells is a complex milieu and unraveling how its unique cytoarchitecture is achieved and maintained is a central theme in modern cell biology. The actin cytoskeleton is essential for the maintenance of cell shape and locomotion, and also provides tracks for active intracellular transport. Myosins, the actin-dependent motor proteins form a superfamily of at least 15 structural classes and have been identified in a wide variety of organisms, making the presence of actin and myosins a hallmark feature of eukaryotes. Direct connections of myosins to a variety of cellular tasks are now emerging, such as in cytokinesis, phagocytosis, endocytosis, polarized secretion and exocytosis, axonal transport. Recent studies reveal that myosins also play an essential role in many aspects of signal transduction and neurosensation.

Affiliation Not a UNIGE publication
Citation (ISO format)
SOLDATI, Thierry, GEISSLER, H, SCHWARZ, E C. Unconventional myosins at the crossroad of signal transduction and cytoskeleton remodeling. In: Protoplasma, 1999, vol. 209, n° 1-2, p. 28–37. doi: 10.1007/BF01415698
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Article (Published version)
ISSN of the journal0033-183X

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