TS
Soldati, Thierry
Affiliation entities
Research groups
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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An evolutionary-conserved VPS34-PIKfyve-TRPML1-Myosin II axis regulates the speed of amoeboid cell migration | 2024 | 18 | 3 | ||||
Discovery of anti-infective compounds against Mycobacterium marinum after biotransformation of simple natural stilbene scaffolds by a fungal secretome | 2024 | 19 | 7 | ||||
Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP | 2024 | 6 | 0 | ||||
Membrane microdomains are crucial for Mycobacterium marinum EsxA-dependent membrane damage, escape to the cytosol and infection | 2024 | 20 | 6 | ||||
Inflicting, Monitoring, Visualizing, and Quantitating Various Sterile Membrane Damages and the Repair Response in Dictyostelium discoideum | Dictyostelium discoideum: Methods and Protocols | 2024 | 20 | 0 | |||
Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals the genetic requirement for virulence and survival in amoebae and microglial cells | MSystems | 2024 | 32 | 5 | |||
Exploring host–pathogen interactions in the Dictyostelium discoideum–Mycobacterium marinum infection model of tuberculosis | Disease models & mechanisms | 2024 | 30 | 13 | |||
Application of the RDF framework to integrate heterogenous experimental data of a large chemo- and biodiverse collection from a research collaborative project | 2023 | 18 | 8 | ||||
A PI(3,5)P2 reporter reveals PIKfyve activity and dynamics on macropinosomes and phagosomes | The journal of cell biology | 2023 | 74 | 10 | |||
A TRAF-like E3 ubiquitin ligase TrafE coordinates ESCRT and autophagy in endolysosomal damage response and cell-autonomous immunity to Mycobacterium marinum | eLife | 2023 | 40 | 34 | |||
Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals genetic requirement for virulence and survival in amoebae and microglial cells | 2023 | 57 | 15 | ||||
Targeted isolation of natural analogs of anti-mycobacterial hit compounds based on the metabolite profiling of a large collection of plant extracts | Frontiers in natural products | 2023 | 23 | 8 | |||
5-ethyl-2’-deoxyuridine fragilizes Klebsiella pneumoniae outer wall and facilitates intracellular killing by phagocytic cells | PloS one | 2022 | 39 | 37 | |||
Conserved mechanisms drive host-lipid access, import, and utilization in Mycobacterium tuberculosis and M. marinum | Biology of Mycobacterial Lipids | 2022 | 33 | 1 | |||
A PI(3,5)P2 probe reveals PIKfyve is required for Rab7 acquisition and the delivery and fusion of early macropinosomes to phagosomes | 2022 | 47 | 16 | ||||
Novel Single-Cell and High-Throughput Microscopy Techniques to Monitor Dictyostelium discoideum–Mycobacterium marinum Infection Dynamics | Mycobacteria Protocols | 2021 | 172 | 0 | |||
The Dictyostelium discoideum E3 ubiquitin ligase TrafE coordinates endolysosomal damage response and cell-autonomous immunity to Mycobacterium marinum | 2021 | 232 | 83 | ||||
Zn2+ Intoxication of Mycobacterium marinum during Dictyostelium discoideum Infection Is Counteracted by Induction of the Pathogen Zn2+ Exporter CtpC | mBio | 2021 | 280 | 134 | |||
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) | Autophagy | 2021 | 237 | 2 | |||
Disruption of vacuolin microdomains in the host Dictyostelium discoideum increases resistance to Mycobacterium marinum -induced membrane damage and infection | 2021 | 232 | 76 | ||||
Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria | Current Biology | 2020 | 303 | 206 | |||
Mycobacterium marinum produces distinct mycobactin and carboxymycobactin siderophores to promote growth in broth and phagocytes | Cellular Microbiology | 2020 | 250 | 0 | |||
Mycobacterium bovis uses the ESX-1 Type VII secretion system to escape predation by the soil-dwelling amoeba Dictyostelium discoideum | ISME Journal | 2020 | 279 | 137 | |||
First-order agent-based models of emergent behaviour of Dictyostelium discoideum and their inspiration for swarm robotics | Artificial Life and Robotics | 2020 | 244 | 78 | |||
Identification of anti-mycobacterium and anti-legionella compounds with potential distinctive structural scaffolds from an HD-PBL using phenotypic screens in amoebae host models | Frontiers in Microbiology | 2020 | 260 | 151 | |||
Conidial Melanin of the Human-Pathogenic Fungus"Aspergillus fumigatus" Disrupts Cell Autonomous Defenses in Amoebae | mBio | 2020 | 305 | 205 | |||
AI842, AI843, AI844 and AI177 antibodies do not recognize a FLAG-tagged protein expressed in D. discoideum by western blot | Antibody Reports | 2020 | 290 | 80 | |||
The RB008 antibody does not recognize D. discoideum NoxA by western blot | Antibody Reports | 2020 | 224 | 70 | |||
Vacuolins and myosin VII are required for phagocytic uptake and phagosomal membrane recycling in Dictyostelium discoideum | Journal of Cell Science | 2020 | 371 | 1 | |||
Second-order agent-based models of emergent behaviour of Dictyostelium discoideum and their inspiration for swarm robotics | Artificial Life and Robotics | 2020 | 231 | 51 | |||
Transcriptional Responses of Dictyostelium discoideum Exposed to Different Classes of Bacteria | Frontiers in Microbiology | 2020 | 217 | 82 | |||
AI842, AI843, AI844 and AI177 antibodies do not recognize a FLAG-tagged protein by immunofluorescence in D. discoideum cells | Antibody Reports | 2020 | 291 | 119 | |||
PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection | PLOS Pathogens | 2019 | 277 | 131 | |||
RB155, RB156 and RB189 antibodies do not recognize the D. discoideum Tsg101 protein by western blot | Antibody Reports | 2019 | 259 | 61 | |||
Antimycobacterial activity in a single-cell infection assay of ellagitannins from Combretum aculeatum and their bioavailable metabolites | Journal of Ethnopharmacology | 2019 | 343 | 2 | |||
The developmental cycle of Dictyostelium discoideum ensures curing of a mycobacterial infection at both cell-autonomous level and by collaborative exclusion | 2019 | 274 | 98 | ||||
Time-resolved RNA-seq profiling of the infection of Dictyostelium discoideum by Mycobacterium marinum reveals an integrated host response to damage and stress | 2019 | 326 | 98 | ||||
A brief historical and evolutionary perspective on the origin of cellular microbiology research | Cellular Microbiology | 2019 | 225 | 125 | |||
Distinct Mycobacterium marinum phosphatases determine pathogen vacuole phosphoinositide pattern, phagosome maturation, and escape to the cytosol | Cellular Microbiology | 2019 | 245 | 0 | |||
Lowe syndrome–linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum | Molecular Biology of the Cell | 2019 | 329 | 131 | |||
Cellular Microbiology 1999–2019 | Cellular Microbiology | 2019 | 207 | 0 | |||
Zn2+ intoxication of Mycobacterium marinum during Dictyostelium discoideum infection is counteracted by induction of the pathogen Zn2+ exporter CtpC | 2019 | 249 | 113 | ||||
Co-ordinated Ras and Rac activity shapes macropinocytic cups and enables phagocytosis of geometrically diverse bacteria | 2019 | 131 | 36 | ||||
Conidial melanin of the human pathogenic fungus Aspergillus fumigatus disrupts cell autonomous defenses in amoebae | 2019 | 252 | 82 | ||||
Lowe Syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum | 2019 | 125 | 55 | ||||
Editorial: Amoebae as Host Models to Study the Interaction With Pathogens | Frontiers in Cellular and Infection Microbiology | 2019 | 197 | 61 | |||
Proteomic characterization of the Mycobacterium marinum-containing vacuole in Dictyostelium discoideum | 2019 | 212 | 110 | ||||
Dictyostelium discoideum flotillin homologues are essential for phagocytosis and participate in plasma membrane recycling and lysosome biogenesis | 2019 | 305 | 198 | ||||
When Dicty Met Myco, a (Not So) Romantic Story about One Amoeba and Its Intracellular Pathogen | Frontiers in Cellular and Infection Microbiology | 2018 | 392 | 213 | |||
Secreted heme peroxidase fromDictyostelium discoideum: Insights into catalysis, structure, and biological role | Journal of Biological Chemistry | 2018 | 402 | 154 | |||
Identification of novel anti-bacterial compounds from a chemically highly diverse pathways-based library using phenotypic screens in amoebae host models | 2018 | 577 | 296 | ||||
The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection | PLOS Pathogens | 2018 | 379 | 141 | |||
ESCRT and autophagy cooperate to repair ESX-1-dependent damage to the Mycobacterium-containing vacuole | 2018 | 220 | 79 | ||||
Localization of all four ZnT zinc transporters in Dictyostelium and impact of ZntA and ZntB knockout on bacteria killing | Journal of Cell Science | 2018 | 378 | 235 | |||
Functions of the Dictyostelium LIMP-2 and CD36 homologues in bacteria uptake, phagolysosome biogenesis and host cell defence | Journal of Cell Science | 2018 | 371 | 155 | |||
Survey on medicinal plants traditionally used in Senegal for the treatment of tuberculosis (TB) and assessment of their antimycobacterial activity | Journal of Ethnopharmacology | 2018 | 486 | 3 | |||
Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets | Scientific Reports | 2018 | 476 | 183 | |||
Eat Prey, Live: Dictyostelium discoideum As a Model for Cell-Autonomous Defenses | Frontiers in Immunology | 2018 | 513 | 390 | |||
The Saposin-Like Protein AplD Displays Pore-Forming Activity and Participates in Defense Against Bacterial Infection During a Multicellular Stage of Dictyostelium discoideum | Frontiers in Cellular and Infection Microbiology | 2018 | 414 | 153 | |||
PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection | 2018 | 178 | 46 | ||||
Vps13F links bacterial recognition and intracellular killing in Dictyostelium | Cellular microbiology | 2017 | 580 | 238 | |||
Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model | PLOS ONE | 2017 | 431 | 208 | |||
Methods to Monitor and Quantify Autophagy in the Social Amoeba Dictyostelium discoideum | Cells | 2017 | 430 | 237 | |||
Breaking fat! How mycobacteria and other intracellular pathogens manipulate host lipid droplets | Biochimie | 2017 | 444 | 0 | |||
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) | Redox Biology | 2017 | 522 | 674 | |||
Mycobacterium marinum Degrades Both Triacylglycerols and Phospholipids from Its Dictyostelium Host to Synthesise Its Own Triacylglycerols and Generate Lipid Inclusions | PLOS pathogens | 2017 | 565 | 235 | |||
Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical model | Autophagy | 2017 | 1 533 | 270 | |||
Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner | PLOS Pathogens | 2017 | 481 | 225 | |||
A microfluidic cell-trapping device for single-cell tracking of host-microbe interactions | Lab on a chip | 2016 | 517 | 5 | |||
Of Amoebae and Men: Extracellular DNA Traps as an Ancient Cell-Intrinsic Defense Mechanism | Frontiers in immunology | 2016 | 536 | 217 | |||
WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 560 | 1 | |||
Social amoebae trap and kill bacteria by casting DNA nets | Nature communications | 2016 | 498 | 244 | |||
Dictyostelium EHD associates with Dynamin and participates in phagosome maturation | Journal of cell science | 2016 | 505 | 221 | |||
In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhA | Journal of medicinal chemistry | 2016 | 598 | 6 | |||
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond | PLOS pathogens | 2016 | 642 | 454 | |||
Potassium Sensitive Optical Nanosensors Containing Voltage Sensitive Dyes | Chimia | 2015 | 551 | 282 | |||
Charged Solvatochromic Dyes as Signal Transducers in pH Independent Fluorescent and Colorimetric Ion Selective Nanosensors | Analytical chemistry | 2015 | 427 | 2 | |||
Lipid droplet dynamics at early stages of Mycobacterium marinum infection in Dictyostelium | Cellular microbiology | 2015 | 515 | 0 | |||
The autophagic machinery ensures nonlytic transmission of mycobacteria | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 573 | 0 | |||
Live imaging of Mycobacterium marinum infection in Dictyostelium discoideum | Methods in molecular biology | 2015 | 634 | 1 | |||
Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila | ACS infectious diseases | 2015 | 616 | 460 | |||
Reactive oxygen species and mitochondria: A nexus of cellular homeostasis | Redox biology | 2015 | 614 | 461 | |||
Adrenergic antagonists restrict replication of Legionella | Microbiology | 2015 | 565 | 0 | |||
Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen system | PloS one | 2014 | 711 | 302 | |||
Setting up and monitoring an infection of Dictyostelium discoideum with mycobacteria | Methods in molecular biology | 2013 | 580 | 0 | |||
WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestion | Molecular biology of the cell | 2013 | 561 | 341 | |||
Quantitative analysis of phagocytosis and phagosome maturation | Methods in molecular biology | 2013 | 561 | 4 | |||
Detecting, visualizing and quantitating the generation of reactive oxygen species in an amoeba model system | Journal of visualized experiments | 2013 | 517 | 190 | |||
Evolution of the ferric reductase domain (FRD) superfamily: modularity, functional diversification, and signature motifs | PloS one | 2013 | 560 | 330 | |||
Exploring Anti-Bacterial Compounds against Intracellular Legionella | PloS one | 2013 | 651 | 340 | |||
The Balance in the Delivery of ER Components and the Vacuolar Proton Pump to the Phagosome Depends on Myosin IK in Dictyostelium | Molecular & cellular proteomics | 2012 | 622 | 0 | |||
Mycobacteria and the intraphagosomal environment: take it with a pinch of salt(s)! | Traffic | 2012 | 621 | 0 | |||
Dynamin A, Myosin IB and Abp1 couple phagosome maturation to F-actin binding | Traffic | 2012 | 600 | 935 | |||
Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 1 084 | 5 335 | |||
Prison break: pathogens' strategies to egress from host cells | Microbiology and molecular biology reviews | 2012 | 643 | 374 | |||
Mucolipin controls lysosome exocytosis in Dictyostelium | Journal of cell science | 2012 | 565 | 294 | |||
Rab8a regulates the exocyst-mediated kiss-and-run discharge of the Dictyostelium contractile vacuole | Molecular biology of the cell | 2012 | 624 | 472 | |||
Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime molds | BMC developmental biology | 2012 | 721 | 366 | |||
How One Cell Eats Another : Principles of Phagocytosis | Systems microbiology : current topics and applications | 2012 | 1 285 | 0 | |||
Role of magnesium and a phagosomal P-type ATPase in intracellular bacterial killing | Cellular microbiology | 2011 | 710 | 407 | |||
Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis | The Journal of cell biology | 2011 | 541 | 435 | |||
Molecular characterization of the evolution of phagosomes | Molecular systems biology | 2010 | 610 | 732 | |||
A myosin IK-Abp1-PakB circuit acts as a switch to regulate phagocytosis efficiency | Molecular biology of the cell | 2010 | 654 | 509 | |||
Mitochondrial translation in absence of local tRNA aminoacylation and methionyl tRNA formylation in Apicomplexa | Molecular microbiology | 2010 | 558 | 0 | |||
Autophagy in Dictyostelium: genes and pathways, cell death and infection | Autophagy | 2010 | 521 | 962 | |||
Infection by tubercular mycobacteria is spread by nonlytic ejection from their amoeba hosts | Science | 2009 | 625 | 691 | |||
Phagosome Proteomes Unite! A Virtual Model of Maturation as a Tool to Study Pathogen-Induced Changes | Intracellular Niches of Microbes: A Microbes Guide Through the Host Cell | 2009 | 476 | 0 | |||
The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization | Chimia | 2009 | 192 | 111 | |||
Mycobacterium marinum | Intracellular Niches of Microbes: A Microbes Guide Through the Host Cell | 2009 | 372 | 0 | |||
Eat, kill or die: when amoeba meets bacteria | Current opinion in microbiology | 2008 | 643 | 12 | |||
Monitoring time-dependent maturation changes in purified phagosomes from Dictyostelium discoideum | Methods in molecular biology | 2008 | 567 | 279 | |||
Dual targeting of antioxidant and metabolic enzymes to the mitochondrion and the apicoplast of Toxoplasma gondii | PLOS pathogens | 2007 | 588 | 339 | |||
Flotillin and RacH modulate the intracellular immunity of Dictyostelium to Mycobacterium marinum infection | Cellular microbiology | 2007 | 568 | 848 | |||
Powering membrane traffic in endocytosis and recycling | Nature reviews. Molecular cell biology | 2006 | 598 | 694 | |||
Optimized fixation and immunofluorescence staining methods for Dictyostelium cells | Methods in molecular biology | 2006 | 596 | 826 | |||
Dissection of amoeboid movement into two mechanically distinct modes | Journal of cell science | 2006 | 604 | 635 | |||
Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake | Molecular & cellular proteomics | 2006 | 554 | 621 | |||
Preparation of intact, highly purified phagosomes from Dictyostelium | Methods in molecular biology | 2006 | 575 | 453 | |||
Involvement of the AP-1 adaptor complex in early steps of phagocytosis and macropinocytosis | Molecular biology of the cell | 2004 | 849 | 0 | |||
Do class I myosins exert their function through regulation of actin dynamics? | Cell Motility: From Molecules to Organisms | 2003 | 508 | 0 | |||
Unconventional myosins, actin dynamics and endocytosis: a ménage à trois? | Traffic | 2003 | 497 | 372 | |||
Morphology and dynamics of the endocytic pathway in Dictyostelium discoideum | Molecular biology of the cell | 2002 | 497 | 341 | |||
High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phases | Molecular biology of the cell | 2002 | 559 | 676 | |||
Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor | EMBO journal | 2002 | 432 | 0 | |||
Toxoplasma gondii myosins B/C: one gene, two tails, two localizations, and a role in parasite division | The Journal of cell biology | 2001 | 432 | 129 | |||
A myosin I is involved in membrane recycling from early endosomes | The Journal of cell biology | 2000 | 546 | 289 | |||
Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells | Biophysical journal | 2000 | 473 | 262 | |||
A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization | Molecular biology of the cell | 2000 | 480 | 714 | |||
Identification of a novel saturable endoplasmic reticulum localization mechanism mediated by the C-terminus of a Dictyostelium protein disulfide isomerase | Molecular biology of the cell | 2000 | 543 | 549 | |||
The tail domain of myosin M catalyses nucleotide exchange on Rac1 GTPases and can induce actin-driven surface protrusions | Traffic | 2000 | 549 | 1 770 | |||
Dictyostelium myosin IK is involved in the maintenance of cortical tension and affects motility and phagocytosis | Journal of cell science | 2000 | 474 | 560 | |||
Molecular mechanisms of membrane trafficking. What do we learn from Dictyostelium discoideum? | Protist | 1999 | 549 | 445 | |||
Production of reagents and optimization of methods for studying calmodulin-binding proteins | Protein expression and purification | 1999 | 543 | 879 | |||
How many is enough? Exploring the myosin repertoire in the model eukaryote Dictyostelium discoideum | Cell biochemistry and biophysics | 1999 | 565 | 902 | |||
A potentially exhaustive screening strategy reveals two novel divergent myosins in Dictyostelium | Cell biochemistry and biophysics | 1999 | 515 | 773 | |||
Unconventional myosins at the crossroad of signal transduction and cytoskeleton remodeling | Protoplasma | 1999 | 526 | 573 | |||
Ethane-freezing/methanol-fixation of cell monolayers: a procedure for improved preservation of structure and antigenicity for light and electron microscopies | Journal of structural biology |