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An evolutionary-conserved VPS34-PIKfyve-TRPML1-Myosin II axis regulates the speed of amoeboid cell migration
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2024 29 7
Discovery of anti-infective compounds against Mycobacterium marinum after biotransformation of simple natural stilbene scaffolds by a fungal secretomeFrontiers
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2024 43 24
Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP
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2024 20 10
Membrane microdomains are crucial for Mycobacterium marinum EsxA-dependent membrane damage, escape to the cytosol and infection
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2024 36 14
Inflicting, Monitoring, Visualizing, and Quantitating Various Sterile Membrane Damages and the Repair Response in Dictyostelium discoideumDictyostelium discoideum: Methods and Protocols
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2024 28 0
Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals the genetic requirement for virulence and survival in amoebae and microglial cellsMSystems
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2024 51 18
Prioritization of Novel Anti-infective Stilbene derivatives by Combining Metabolomic Data Organization and a Stringent 3R-infection Model in a Knowledge Graph
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2024 46 19
Exploring host–pathogen interactions in the Dictyostelium discoideum–Mycobacterium marinum infection model of tuberculosisDisease models & mechanisms
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2024 39 44
Application of the RDF framework to integrate heterogenous experimental data of a large chemo- and biodiverse collection from a research collaborative project
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2023 46 20
A PI(3,5)P2 reporter reveals PIKfyve activity and dynamics on macropinosomes and phagosomesThe journal of cell biology
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2023 114 19
A TRAF-like E3 ubiquitin ligase TrafE coordinates ESCRT and autophagy in endolysosomal damage response and cell-autonomous immunity to Mycobacterium marinumeLife
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2023 58 41
Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals genetic requirement for virulence and survival in amoebae and microglial cells
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2023 72 19
Targeted isolation of natural analogs of anti-mycobacterial hit compounds based on the metabolite profiling of a large collection of plant extractsFrontiers in natural products
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2023 33 14
5-ethyl-2’-deoxyuridine fragilizes Klebsiella pneumoniae outer wall and facilitates intracellular killing by phagocytic cellsPloS one
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2022 48 43
Conserved mechanisms drive host-lipid access, import, and utilization in Mycobacterium tuberculosis and M. marinumBiology of Mycobacterial Lipids
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2022 43 1
A PI(3,5)P2 probe reveals PIKfyve is required for Rab7 acquisition and the delivery and fusion of early macropinosomes to phagosomes
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2022 65 27
Novel Single-Cell and High-Throughput Microscopy Techniques to Monitor Dictyostelium discoideum–Mycobacterium marinum Infection DynamicsMycobacteria Protocols
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2021 183 0
The Dictyostelium discoideum E3 ubiquitin ligase TrafE coordinates endolysosomal damage response and cell-autonomous immunity to Mycobacterium marinum
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2021 247 98
Zn2+ Intoxication of Mycobacterium marinum during Dictyostelium discoideum Infection Is Counteracted by Induction of the Pathogen Zn2+ Exporter CtpCmBio
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2021 292 140
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)Autophagy
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2021 256 2
Disruption of vacuolin microdomains in the host Dictyostelium discoideum increases resistance to Mycobacterium marinum -induced membrane damage and infection
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2021 251 88
Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse BacteriaCurrent Biology
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2020 315 210
Mycobacterium marinum produces distinct mycobactin and carboxymycobactin siderophores to promote growth in broth and phagocytesCellular Microbiology
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2020 258 0
Mycobacterium bovis uses the ESX-1 Type VII secretion system to escape predation by the soil-dwelling amoeba Dictyostelium discoideumISME Journal
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2020 296 146
First-order agent-based models of emergent behaviour of Dictyostelium discoideum and their inspiration for swarm roboticsArtificial Life and Robotics
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2020 254 88
Identification of anti-mycobacterium and anti-legionella compounds with potential distinctive structural scaffolds from an HD-PBL using phenotypic screens in amoebae host modelsFrontiers in Microbiology
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2020 283 165
Conidial Melanin of the Human-Pathogenic Fungus"Aspergillus fumigatus" Disrupts Cell Autonomous Defenses in AmoebaemBio
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2020 320 209
AI842, AI843, AI844 and AI177 antibodies do not recognize a FLAG-tagged protein expressed in D. discoideum by western blotAntibody Reports
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2020 306 86
The RB008 antibody does not recognize D. discoideum NoxA by western blotAntibody Reports
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2020 236 78
Vacuolins and myosin VII are required for phagocytic uptake and phagosomal membrane recycling in Dictyostelium discoideumJournal of Cell Science
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2020 389 1
Second-order agent-based models of emergent behaviour of Dictyostelium discoideum and their inspiration for swarm roboticsArtificial Life and Robotics
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2020 241 60
Transcriptional Responses of Dictyostelium discoideum Exposed to Different Classes of BacteriaFrontiers in Microbiology
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2020 237 93
AI842, AI843, AI844 and AI177 antibodies do not recognize a FLAG-tagged protein by immunofluorescence in D. discoideum cellsAntibody Reports
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2020 314 139
PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infectionPLOS Pathogens
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2019 289 134
RB155, RB156 and RB189 antibodies do not recognize the D. discoideum Tsg101 protein by western blotAntibody Reports
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2019 269 64
Antimycobacterial activity in a single-cell infection assay of ellagitannins from Combretum aculeatum and their bioavailable metabolitesJournal of Ethnopharmacology
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2019 359 2
The developmental cycle of Dictyostelium discoideum ensures curing of a mycobacterial infection at both cell-autonomous level and by collaborative exclusion
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2019 294 104
Time-resolved RNA-seq profiling of the infection of Dictyostelium discoideum by Mycobacterium marinum reveals an integrated host response to damage and stress
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2019 349 105
A brief historical and evolutionary perspective on the origin of cellular microbiology researchCellular Microbiology
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2019 239 136
Distinct Mycobacterium marinum phosphatases determine pathogen vacuole phosphoinositide pattern, phagosome maturation, and escape to the cytosolCellular Microbiology
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2019 257 0
Lowe syndrome–linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideumMolecular Biology of the Cell
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2019 345 139
Cellular Microbiology 1999–2019Cellular Microbiology
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2019 215 0
Zn2+ intoxication of Mycobacterium marinum during Dictyostelium discoideum infection is counteracted by induction of the pathogen Zn2+ exporter CtpC
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2019 264 115
Co-ordinated Ras and Rac activity shapes macropinocytic cups and enables phagocytosis of geometrically diverse bacteria
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2019 142 37
Conidial melanin of the human pathogenic fungus Aspergillus fumigatus disrupts cell autonomous defenses in amoebae
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2019 263 86
Lowe Syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum
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2019 134 62
Editorial: Amoebae as Host Models to Study the Interaction With PathogensFrontiers in Cellular and Infection Microbiology
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2019 209 67
Proteomic characterization of the Mycobacterium marinum-containing vacuole in Dictyostelium discoideum
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2019 232 114
Dictyostelium discoideum flotillin homologues are essential for phagocytosis and participate in plasma membrane recycling and lysosome biogenesis
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2019 325 206
When Dicty Met Myco, a (Not So) Romantic Story about One Amoeba and Its Intracellular PathogenFrontiers in Cellular and Infection Microbiology
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2018 405 227
Secreted heme peroxidase fromDictyostelium discoideum: Insights into catalysis, structure, and biological roleJournal of Biological Chemistry
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2018 425 162
Identification of novel anti-bacterial compounds from a chemically highly diverse pathways-based library using phenotypic screens in amoebae host models
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2018 587 310
The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infectionPLOS Pathogens
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2018 393 146
ESCRT and autophagy cooperate to repair ESX-1-dependent damage to the Mycobacterium-containing vacuole
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2018 230 87
Localization of all four ZnT zinc transporters in Dictyostelium and impact of ZntA and ZntB knockout on bacteria killingJournal of Cell Science
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2018 396 239
Functions of the Dictyostelium LIMP-2 and CD36 homologues in bacteria uptake, phagolysosome biogenesis and host cell defenceJournal of Cell Science
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2018 386 183
Survey on medicinal plants traditionally used in Senegal for the treatment of tuberculosis (TB) and assessment of their antimycobacterial activityJournal of Ethnopharmacology
accessLevelRestricted
2018 502 3
Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targetsScientific Reports
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2018 492 190
Eat Prey, Live: Dictyostelium discoideum As a Model for Cell-Autonomous DefensesFrontiers in Immunology
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2018 529 413
The Saposin-Like Protein AplD Displays Pore-Forming Activity and Participates in Defense Against Bacterial Infection During a Multicellular Stage of Dictyostelium discoideumFrontiers in Cellular and Infection Microbiology
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2018 425 155
PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection
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2018 214 53
Vps13F links bacterial recognition and intracellular killing in DictyosteliumCellular microbiology
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2017 612 250
Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host modelPLOS ONE
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2017 450 211
Methods to Monitor and Quantify Autophagy in the Social Amoeba Dictyostelium discoideumCells
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2017 445 240
Breaking fat! How mycobacteria and other intracellular pathogens manipulate host lipid dropletsBiochimie
accessLevelRestricted
2017 459 0
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)Redox Biology
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2017 544 697
Mycobacterium marinum Degrades Both Triacylglycerols and Phospholipids from Its Dictyostelium Host to Synthesise Its Own Triacylglycerols and Generate Lipid InclusionsPLOS pathogens
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2017 583 240
Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical modelAutophagy
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2017 1,551 282
Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent mannerPLOS Pathogens
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2017 497 318
A microfluidic cell-trapping device for single-cell tracking of host-microbe interactionsLab on a chip
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2016 533 5
Of Amoebae and Men: Extracellular DNA Traps as an Ancient Cell-Intrinsic Defense MechanismFrontiers in immunology
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2016 558 236
WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptorsProceedings of the National Academy of Sciences of the United States of America
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2016 578 1
Social amoebae trap and kill bacteria by casting DNA netsNature communications
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2016 513 260
Dictyostelium EHD associates with Dynamin and participates in phagosome maturationJournal of cell science
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2016 519 229
In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhAJournal of medicinal chemistry
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2016 613 6
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and BeyondPLOS pathogens
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2016 662 470
Potassium Sensitive Optical Nanosensors Containing Voltage Sensitive DyesChimia
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2015 570 287
Charged Solvatochromic Dyes as Signal Transducers in pH Independent Fluorescent and Colorimetric Ion Selective NanosensorsAnalytical chemistry
accessLevelRestricted
2015 447 2
Lipid droplet dynamics at early stages of Mycobacterium marinum infection in DictyosteliumCellular microbiology
accessLevelRestricted
2015 527 0
The autophagic machinery ensures nonlytic transmission of mycobacteriaProceedings of the National Academy of Sciences of the United States of America
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2015 582 0
Live imaging of Mycobacterium marinum infection in Dictyostelium discoideumMethods in molecular biology
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2015 641 1
Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophilaACS infectious diseases
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2015 636 468
Reactive oxygen species and mitochondria: A nexus of cellular homeostasisRedox biology
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2015 631 490
Adrenergic antagonists restrict replication of LegionellaMicrobiology
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2015 578 0
Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen systemPloS one
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2014 724 314
Setting up and monitoring an infection of Dictyostelium discoideum with mycobacteriaMethods in molecular biology
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2013 594 0
WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestionMolecular biology of the cell
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2013 581 347
Quantitative analysis of phagocytosis and phagosome maturationMethods in molecular biology
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2013 578 4
Detecting, visualizing and quantitating the generation of reactive oxygen species in an amoeba model systemJournal of visualized experiments
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2013 549 207
Evolution of the ferric reductase domain (FRD) superfamily: modularity, functional diversification, and signature motifsPloS one
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2013 583 333
Exploring Anti-Bacterial Compounds against Intracellular LegionellaPloS one
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2013 660 343
The Balance in the Delivery of ER Components and the Vacuolar Proton Pump to the Phagosome Depends on Myosin IK in DictyosteliumMolecular & cellular proteomics
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2012 641 0
Mycobacteria and the intraphagosomal environment: take it with a pinch of salt(s)!Traffic
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2012 628 0
Dynamin A, Myosin IB and Abp1 couple phagosome maturation to F-actin bindingTraffic
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2012 614 941
Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy
accessLevelPublic
2012 1,097 5,336
Prison break: pathogens' strategies to egress from host cellsMicrobiology and molecular biology reviews
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2012 668 382
Mucolipin controls lysosome exocytosis in DictyosteliumJournal of cell science
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2012 592 322
Rab8a regulates the exocyst-mediated kiss-and-run discharge of the Dictyostelium contractile vacuoleMolecular biology of the cell
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2012 637 477
Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime moldsBMC developmental biology
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2012 743 373
How One Cell Eats Another : Principles of PhagocytosisSystems microbiology : current topics and applications
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2012 1,307 0
Role of magnesium and a phagosomal P-type ATPase in intracellular bacterial killingCellular microbiology
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2011 725 414
Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosisThe Journal of cell biology
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2011 553 438
Molecular characterization of the evolution of phagosomesMolecular systems biology
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2010 630 734
A myosin IK-Abp1-PakB circuit acts as a switch to regulate phagocytosis efficiencyMolecular biology of the cell
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2010 664 528
Mitochondrial translation in absence of local tRNA aminoacylation and methionyl tRNA formylation in ApicomplexaMolecular microbiology
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2010 571 0
Autophagy in Dictyostelium: genes and pathways, cell death and infectionAutophagy
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2010 534 977
Infection by tubercular mycobacteria is spread by nonlytic ejection from their amoeba hostsScience
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2009 639 738
Phagosome Proteomes Unite! A Virtual Model of Maturation as a Tool to Study Pathogen-Induced ChangesIntracellular Niches of Microbes: A Microbes Guide Through the Host Cell
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2009 495 0
The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular OrganizationChimia
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2009 214 123
Mycobacterium marinumIntracellular Niches of Microbes: A Microbes Guide Through the Host Cell
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2009 384 0
Eat, kill or die: when amoeba meets bacteriaCurrent opinion in microbiology
accessLevelRestricted
2008 666 12
Monitoring time-dependent maturation changes in purified phagosomes from Dictyostelium discoideumMethods in molecular biology
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2008 576 295
Dual targeting of antioxidant and metabolic enzymes to the mitochondrion and the apicoplast of Toxoplasma gondiiPLOS pathogens
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2007 624 351
Flotillin and RacH modulate the intracellular immunity of Dictyostelium to Mycobacterium marinum infectionCellular microbiology
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2007 587 858
Powering membrane traffic in endocytosis and recyclingNature reviews. Molecular cell biology
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2006 629 713
Optimized fixation and immunofluorescence staining methods for Dictyostelium cellsMethods in molecular biology
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2006 603 874
Dissection of amoeboid movement into two mechanically distinct modesJournal of cell science
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2006 627 652
Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptakeMolecular & cellular proteomics
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2006 570 626
Preparation of intact, highly purified phagosomes from DictyosteliumMethods in molecular biology
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2006 585 466
Involvement of the AP-1 adaptor complex in early steps of phagocytosis and macropinocytosisMolecular biology of the cell
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2004 860 0
Do class I myosins exert their function through regulation of actin dynamics?Cell Motility: From Molecules to Organisms
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2003 516 0
Unconventional myosins, actin dynamics and endocytosis: a ménage à trois?Traffic
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2003 515 382
Morphology and dynamics of the endocytic pathway in Dictyostelium discoideumMolecular biology of the cell
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2002 506 355
High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phasesMolecular biology of the cell
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2002 579 684
Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motorEMBO journal
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2002 442 0
Toxoplasma gondii myosins B/C: one gene, two tails, two localizations, and a role in parasite divisionThe Journal of cell biology
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2001 443 138
A myosin I is involved in membrane recycling from early endosomesThe Journal of cell biology
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2000 554 297
Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cellsBiophysical journal
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2000 485 268
A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localizationMolecular biology of the cell
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2000 491 730
Identification of a novel saturable endoplasmic reticulum localization mechanism mediated by the C-terminus of a Dictyostelium protein disulfide isomeraseMolecular biology of the cell
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2000 559 560
The tail domain of myosin M catalyses nucleotide exchange on Rac1 GTPases and can induce actin-driven surface protrusionsTraffic
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2000 570 1,786
Dictyostelium myosin IK is involved in the maintenance of cortical tension and affects motility and phagocytosisJournal of cell science
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2000 495 593
Molecular mechanisms of membrane trafficking. What do we learn from Dictyostelium discoideum?Protist
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1999 579 465
Production of reagents and optimization of methods for studying calmodulin-binding proteinsProtein expression and purification
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1999 561 892
How many is enough? Exploring the myosin repertoire in the model eukaryote Dictyostelium discoideumCell biochemistry and biophysics
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1999 580 928
A potentially exhaustive screening strategy reveals two novel divergent myosins in DictyosteliumCell biochemistry and biophysics
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1999 529 780
Unconventional myosins at the crossroad of signal transduction and cytoskeleton remodelingProtoplasma
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1999 535 589
Ethane-freezing/methanol-fixation of cell monolayers: a procedure for improved preservation of structure and antigenicity for light and electron microscopiesJournal of structural biology
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1998 598 1,475
Dictyostelium discoideum protein disulfide isomerase, an endoplasmic reticulum resident enzyme lacking a KDEL-type retrieval signalFEBS letters
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1997 590 328
Ca2+-triggered peptide secretion in single cells imaged with green fluorescent protein and evanescent-wave microscopyNeuron
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1997 601 959
The intracompartmental sorting of myosin alkali light chain isoproteins reflects the sequence of developmental expression as determined by double epitope-tagging competitionJournal of cell science
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1996 653 378
Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processesThe Journal of biological chemistry
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1995 632 492
Reconstitution of Rab9 endosomal targeting and nucleotide exchange using purified Rab9-GDP dissociation inhibitor complexes and endosome-enriched membranesMethods in enzymology
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1995 518 665
Rab GDP dissociation inhibitor: putting rab GTPases in the right placeThe Journal of biological chemistry
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1995 528 184
Expression of Rab9 protein in Escherichia coli: purification and isoprenylation in vitroMethods in enzymology
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1995 568 480
Dominant negative effect of cytoplasmic actin isoproteins on cardiomyocyte cytoarchitecture and functionThe Journal of cell biology
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1995 493 377
Selective membrane recruitment of Rab GTPasesCold Spring Harbor Symposia on Quantitative Biology
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1995 558 367
Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchangeNature
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1994 572 356
Rab-GDI presents functional Rab9 to the intracellular transport machinery and contributes selectivity to Rab9 membrane recruitmentThe Journal of biological chemistry
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1994 552 186
Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi networkThe Journal of cell biology
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1994 580 369
Rab GDI: a solubilizing and recycling factor for rab9 proteinMolecular biology of the cell
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1993 607 360
Rab9 functions in transport between late endosomes and the trans Golgi networkEMBO journal
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1993 558 457
Transport from late endosomes to trans-Golgi network in semiintact cell extractsMethods in enzymology
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1992 561 340
Molecular analysis of protein sorting during biogenesis of muscle cytoarchitectureSymposia of the Society for Experimental Biology
1992 493 0
Intracompartmental sorting of essential myosin light chains: molecular dissection and in vivo monitoring by epitope taggingCell
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1991 606 547
A unique chicken B-creatine kinase gene gives rise to two B-creatine kinase isoproteins with distinct N termini by alternative splicingThe Journal of biological chemistry
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1990 532 279
Phosphorylation of chicken brain-type creatine kinase affects a physiologically important kinetic parameter and gives rise to protein microheterogeneity in vivoFEBS letters
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1990 587 539
Alternative ribosomal initiation gives rise to chicken brain-type creatine kinase isoproteins with heterogeneous amino terminiThe Journal of biological chemistry
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1990 513 196
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