Nosocomial myiasis is seldom reported in Europe, and intensive care unit (ICU)-acquired myiasis is even rarer. Here, we describe the first report of hospital-acquired oral myiasis caused by Lucilia sericata occurring in a Swiss ICU. We provide a review of all European cases of oral ICU-acquired myiasis published since 1997 and discuss entomological aspects as well as treatment and prevention of this entity.