Scientific article

English

Isavuconazole for the Treatment of Fungal Infections : A Real-life Experience From the Fungal Infection Network of Switzerland (FUNGINOS)

ContributorsCouchepin, Jade; Reinhold, Ilana

; Kronig, Ilona; Guidi, Monia

; Buclin, Thierry

; Schreiber, Peter W; Neofytos, Dionysios

; Lamoth, Frederic

; Fungal Infection Network of Switzerland (FUNGINOS)

CollaboratorsBergeron, Anne; Landis, Basile Nicolas; Riat, Arnaud

Published inOpen forum infectious diseases, vol. 11, no. 5, ofae223

Publication date2024-05

First online date2024-04-26

Abstract

This analysis of 116 isavuconazole therapy courses shows that hepatic test disturbances (HTDs) were relatively frequent (29% of cases) but rarely led to treatment interruption (5%). Importantly, patients with baseline HTDs, including those attributed to a first-line triazole, did not exhibit a higher risk of subsequent HTD under isavuconazole therapy.

Keywords

Aspergillosis
Hepatotoxicity
Liver
Mucormycosis
Triazoles

Affiliation entities

Research groups

Maladies interstitielles et de l'immunodéprimé (1057)

Citation (ISO format)

COUCHEPIN, Jade et al. Isavuconazole for the Treatment of Fungal Infections : A Real-life Experience From the Fungal Infection Network of Switzerland (FUNGINOS). In: Open forum infectious diseases, 2024, vol. 11, n° 5, p. ofae223. doi: 10.1093/ofid/ofae223

Article (Published version)

Identifiers

PID : unige:180735
DOI : 10.1093/ofid/ofae223
PMID : 38756765
PMCID : PMC11097116

Additional URL for this publicationhttps://academic.oup.com/ofid/article/11/5/ofae223/7658664

Journal ISSN2328-8957

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