Migrant workers, particularly undocumented migrants, may be constrained to accept ‘dirty work’. This term refers to poorly paid jobs with long working hours and significant exposure to various risks, potentially affecting their health. While many scholars discuss the health-related risks associated with these work conditions, empirical quantitative evidence is scarce regarding their direct effects on health among undocumented and newly regularized migrants. Consequently, we have formulated the following research question: Does ‘dirty work’ have an influence on the self-rated health of undocumented and newly regularized migrants over time? To answer this question, we utilized a dataset collected during an exceptional regularization procedure in the Swiss Canton of Geneva. Through surveys conducted across four waves, we demonstrate the direct and indirect effects of work conditions on migrants’ health using both random effects and fixed effects models. Our operationalization of ‘dirty work’ reveals that exposure to physically demanding positions has a direct, negative impact on migrants’ self-rated health. This result holds independently of the development of chronic health conditions over time. Our study confirms the existence of a relationship between occupational risks and health and underscores the significance of residence status in this context.