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Scientific article
Review
English

Adventures of a pore-forming toxin at the target cell surface

Published inTrends in microbiology, vol. 8, no. 4, p. 168-172
Publication date2000-04
Abstract

The past three years have shed light on how the pore-forming toxin aerolysin binds to its target cell and then hijacks cellular devices to promote its own polymerization and pore formation. This selective permeabilization of the plasma membrane has unexpected intracellular consequences that might explain the importance of aerolysin in Aeromonas pathogenicity.

eng
Keywords
  • Aerolysin
  • Aeromonas
  • GPI
  • Rafts
  • Toxin
  • Pore forming
  • Endoplasmic reticulum
Citation (ISO format)
ABRAMI, Laurence, FIVAZ, Marc, VAN DER GOOT GRUNBERG, Françoise G. Adventures of a pore-forming toxin at the target cell surface. In: Trends in microbiology, 2000, vol. 8, n° 4, p. 168–172. doi: 10.1016/S0966-842X(00)01722-4
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ISSN of the journal0966-842X
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