MicroRNA-92a-CPEB3 axis protects neurons against inflammatory neurodegeneration
ContributorsWinkler, Iris ; Engler, Jan Broder ; Vieira, Vanessa; Bauer, Simone ; Liu, Yi-Hsiang; Di Liberto, Giovanni ; Grochowska, Katarzyna M; Wagner, Ingrid ; Bier, Jasmina ; Bal, Lukas C ; Rothammer, Nicola; Meurs, Nina ; Egervari, Kristof Levente ; Schattling, Benjamin ; Salinas, Gabriela; Kreutz, Michael R; Huang, Yi-Shuian ; Pless, Ole ; Merkler, Doron ; Friese, Manuel A
Published inScience advances, vol. 9, no. 47, eadi6855
Publication date2023-11-24
First online date2023-11-24
Abstract
Keywords
- Humans
- Mice
- Animals
- MicroRNAs / genetics
- MicroRNAs / metabolism
- Neuroinflammatory Diseases
- Encephalomyelitis, Autoimmune, Experimental / genetics
- Encephalomyelitis, Autoimmune, Experimental / metabolism
- Multiple Sclerosis
- Inflammation / genetics
- Inflammation / metabolism
- Neurons / metabolism
- RNA, Messenger / metabolism
- Mice, Inbred C57BL
- RNA-Binding Proteins / genetics
- RNA-Binding Proteins / metabolism
Affiliation entities
Research groups
Funding
- Swiss National Science Foundation - Deciphering transcriptional regulators of T cell fate decisions in CNS autoimmunity [201271]
- Swiss National Science Foundation - Drivers and signatures of neuronal dysfunction in neuroinflammation [185321]
- European Commission - Molecular pathology of anti-viral T cell responses in the central nervous system [865026]
Citation (ISO format)
WINKLER, Iris et al. MicroRNA-92a-CPEB3 axis protects neurons against inflammatory neurodegeneration. In: Science advances, 2023, vol. 9, n° 47, p. eadi6855. doi: 10.1126/sciadv.adi6855
Main files (1)
Article (Published version)
Secondary files (2)
Identifiers
- PID : unige:173630
- DOI : 10.1126/sciadv.adi6855
- PMID : 38000031
- PMCID : PMC10672163
ISSN of the journal2375-2548