Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases
ContributorsNutma, Erik![orcid](assets/images/orcid.png)
; Fancy, Nurun![orcid](assets/images/orcid.png)
; Weinert, Maria![orcid](assets/images/orcid.png)
; Tsartsalis, Stergios![orcid](assets/images/orcid.png)
; Marzin, Manuel C.; Muirhead, Robert C. J.; Falk, Irene; Breur, Marjolein; de Bruin, Joy; Hollaus, David; Pieterman, Robin; Anink, Jasper; Story, David; Chandran, Siddharthan; Tang, Jiabin; Trolese, Maria C.![orcid](assets/images/orcid.png)
; Saito, Takashi![orcid](assets/images/orcid.png)
; Saido, Takaomi C.; Wiltshire, Katharine H.; Beltran-Lobo, Paula; Phillips, Alexandra; Antel, Jack![orcid](assets/images/orcid.png)
; Healy, Luke![orcid](assets/images/orcid.png)
; Dorion, Marie-France; Galloway, Dylan A.; Benoit, Rochelle Y.; Amosse, Quentin![orcid](assets/images/orcid.png)
; Ceyzeriat, Kelly; Badina, Aurélien Matthieu![orcid](assets/images/orcid.png)
; Kovari, Eniko Veronika; Bendotti, Caterina![orcid](assets/images/orcid.png)
; Aronica, Eleonora![orcid](assets/images/orcid.png)
; Radulescu, Carola I.; Wong, Jia Hui![orcid](assets/images/orcid.png)
; Barron, Anna M.![orcid](assets/images/orcid.png)
; Smith, Amy M.; Barnes, Samuel J.![orcid](assets/images/orcid.png)
; Hampton, David W.; van der Valk, Paul; Jacobson, Steven; Howell, Owain W.; Baker, David; Kipp, Markus![orcid](assets/images/orcid.png)
; Kaddatz, Hannes![orcid](assets/images/orcid.png)
; Tournier, Benjamin![orcid](assets/images/orcid.png)
; Millet, Philippe![orcid](assets/images/orcid.png)
; Matthews, Paul M.![orcid](assets/images/orcid.png)
; Moore, Craig S.![orcid](assets/images/orcid.png)
; Amor, Sandra; Owen, David R.![orcid](assets/images/orcid.png)
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Published inNature communications, vol. 14, no. 1, 5247
Publication date2023-08-28
First online date2023-08-28
Abstract
Research group
Funding
- UK Research and Innovation - The Role of 18kDa Translocator Protein (TSPO) in cellular bioenergetics and microglial activation [MR/N008219/1]
- Swiss National Science Foundation - Molecular Imaging of Neuroinflammation in Bipolar Disorder: a Translational Validation of the TSPO Quantification Methodology [184713]
- Swiss National Science Foundation - TSPO in astrocytes and microglia: role and therapeutic potential in Alzheimer’s disease. [212322]
- Swiss National Science Foundation - Transcriptomic investigation of microglia and astrocytes in Alzheimer’s disease: a human brain post-mortem single-nucleus RNA sequencing study [191446]
Citation (ISO format)
NUTMA, Erik et al. Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases. In: Nature communications, 2023, vol. 14, n° 1, p. 5247. doi: 10.1038/s41467-023-40937-z
Main files (1)
Article (Published version)
Secondary files (5)
Identifiers
- PID : unige:170999
- DOI : 10.1038/s41467-023-40937-z
- PMID : 37640701
Commercial URLhttps://www.nature.com/articles/s41467-023-40937-z
ISSN of the journal2041-1723