Caution when using 1,3, β-D-glucan in the CSF as a biomarker of <i>Candida albicans</i> meningitis

Barbolini, Laura; Riat, Arnaud; Van Delden, Christian; Schrenzel, Jacques

doi:10.1016/j.ijid.2022.06.033

Scientific article

Open access

English

Caution when using 1,3, β-D-glucan in the CSF as a biomarker of Candida albicans meningitis

ContributorsBarbolini, Laura; Riat, Arnaud

; Van Delden, Christian; Schrenzel, Jacques

Published inInternational journal of infectious diseases, vol. 122, p. 531-533

Publication date2022-09

First online date2022-06-26

Abstract

Relying on a biomarker to diagnose or follow up the treatment of a Candida albicans meningitis would have an impact on patient management. The biomarker 1,3, β-D-glucan (BDG), developed for serum testing, shows inconsistent values when applied on cerebrospinal fluid (CSF), and its use with the current protocol on CSF samples warrants caution.

Keywords

Biomarkers
Candida albicans
Humans
Meningitis
Proteoglycans
Beta-Glucans

Affiliation

Faculté de médecine / Section de médecine clinique / Département de médecine

Research group

Citation (ISO format)

BARBOLINI, Laura et al. Caution when using 1,3, β-D-glucan in the CSF as a biomarker of <i>Candida albicans</i> meningitis. In: International journal of infectious diseases, 2022, vol. 122, p. 531–533. doi: 10.1016/j.ijid.2022.06.033

Article (Published version)

CC BY-4.0

Identifiers

PID : unige:168960
DOI : 10.1016/j.ijid.2022.06.033
PMID : 35760379

Commercial URLhttps://linkinghub.elsevier.com/retrieve/pii/S1201971222003691

ISSN of the journal1201-9712

9views

4downloads

Creation01/05/2023 2:38:58 PM

First validation05/22/2023 3:43:30 PM

Update time05/22/2023 4:01:38 PM

Status update05/22/2023 4:01:38 PM

Last indexation08/31/2023 11:15:56 AM

Archive ouverte UNIGE

Caution when using 1,3, β-D-glucan in the CSF as a biomarker of Candida albicans meningitis

Technical informations