Scientific article
Open access

B vitamin supply in plants and humans: the importance of vitamer homeostasis

Published inPlant journal, vol. 111, no. 3, p. 662-682
Publication date2022-08
First online date2022-06-27

B vitamins are a group of water-soluble micronutrients that are required in all life forms. With the lack of biosynthetic pathways, humans depend on dietary uptake of these compounds, either directly or indirectly, from plant sources. B vitamins are frequently given little consideration beyond their role as enzyme accessory factors and are assumed not to limit metabolism. However, it should be recognized that each individual B vitamin is a family of compounds (vitamers), the regulation of which has dedicated pathways. Moreover, it is becoming increasingly evident that individual family members have physiological relevance and should not be sidelined. Here, we elaborate on the known forms of vitamins B1, B6and B9, their distinct functions and importance to metabolism, in both human and plant health, and highlight the relevance of vitamer homeostasis. Research on B vitamin metabolism over the past several years indicates that not only the total level of vitamins but also the oft-neglected homeostasis of the various vitamers of each B vitamin is essential to human and plant health. We briefly discuss the potential of plant biology studies in supporting human health regarding these B vitamins as essential micronutrients. Based on the findings of the past few years we conclude that research should focus on the significance of vitamer homeostasis - at the organ, tissue and subcellular levels - which could improve the health of not only humans but also plants, benefiting from cross-disciplinary approaches and novel technologies.

  • B vitamins
  • Coenzymes
  • Homeostasis
  • Human health
  • Plant health
  • Vitamer
  • Biosynthetic Pathways
  • Humans
  • Micronutrients
  • Plants / metabolism
  • Vitamin B Complex / metabolism
Citation (ISO format)
LIU, Zeguang et al. B vitamin supply in plants and humans: the importance of vitamer homeostasis. In: Plant journal, 2022, vol. 111, n° 3, p. 662–682. doi: 10.1111/tpj.15859
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Article (Published version)
ISSN of the journal0960-7412

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