B vitamin supply in plants and humans: the importance of vitamer homeostasis

Article Article scientifique Revue de la littérature B vitamin supply in plants and humans: the importance of vitamer homeostasis eng 2022-06-27 2022-08 author Liu Zeguang 0000-0002-2454-5043 Vitamins and Environmental Stress Responses in Plants, Department of Botany and Plant Biology, University of Geneva, Quai Ernest-Ansermet 30, CH-1211, Geneva 4, Switzerland. 936186 Département des sciences végétales (BIVEG) author Farkas Peter 0000-0002-1700-2948 Vitamins and Environmental Stress Responses in Plants, Department of Botany and Plant Biology, University of Geneva, Quai Ernest-Ansermet 30, CH-1211, Geneva 4, Switzerland. 869930 Département des sciences végétales (BIVEG) Péter Farkas author Wang Kai 0000-0001-8592-0970 Vitamins and Environmental Stress Responses in Plants, Department of Botany and Plant Biology, University of Geneva, Quai Ernest-Ansermet 30, CH-1211, Geneva 4, Switzerland. 938134 Département des sciences végétales (BIVEG) author Kohli Morgan-Océane Franciszka Vitamins and Environmental Stress Responses in Plants, Department of Botany and Plant Biology, University of Geneva, Quai Ernest-Ansermet 30, CH-1211, Geneva 4, Switzerland. 905675 author Fitzpatrick Thérésa Bridget 0000-0001-7694-5631 Vitamins and Environmental Stress Responses in Plants, Department of Botany and Plant Biology, University of Geneva, Quai Ernest-Ansermet 30, CH-1211, Geneva 4, Switzerland. 684438 Département des sciences végétales (BIVEG) 662-682 10.1111/tpj.15859 35673947 0960-7412 PMC9544542 B vitamins are a group of water-soluble micronutrients that are required in all life forms. With the lack of biosynthetic pathways, humans depend on dietary uptake of these compounds, either directly or indirectly, from plant sources. B vitamins are frequently given little consideration beyond their role as enzyme accessory factors and are assumed not to limit metabolism. However, it should be recognized that each individual B vitamin is a family of compounds (vitamers), the regulation of which has dedicated pathways. Moreover, it is becoming increasingly evident that individual family members have physiological relevance and should not be sidelined. Here, we elaborate on the known forms of vitamins B1, B6and B9, their distinct functions and importance to metabolism, in both human and plant health, and highlight the relevance of vitamer homeostasis. Research on B vitamin metabolism over the past several years indicates that not only the total level of vitamins but also the oft-neglected homeostasis of the various vitamers of each B vitamin is essential to human and plant health. We briefly discuss the potential of plant biology studies in supporting human health regarding these B vitamins as essential micronutrients. Based on the findings of the past few years we conclude that research should focus on the significance of vitamer homeostasis - at the organ, tissue and subcellular levels - which could improve the health of not only humans but also plants, benefiting from cross-disciplinary approaches and novel technologies. B vitamins Coenzymes Homeostasis Human health Plant health Vitamer Biosynthetic Pathways Humans Micronutrients Plants / metabolism Vitamin B Complex / metabolism Dewey 580 Swiss National Science Foundation Dissecting the role of vitamin B1 derivatives and the interaction between vitamin B1 homeostasis and the circadian clock. 162555 CH Projects 45 Département des sciences végétales 163 false Plant journal 111 3 9638e06f-2bbe-44de-ad23-8c0586d1aba5 Article (Published version) Public Article-scientifique-from-europePmc.pdf 4110506 application/pdf CC BY-NC-ND b5f2a8a78f4f33cca574db6aee577a02162af2a79aec36ead93006eb3268887c openAccess Faculté des sciences / Section de biologie / Département des sciences végétales

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B vitamin supply in plants and humans: the importance of vitamer homeostasis	Plant journal			2022	95	345

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