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Scientific article
Open access
French

Le contrôle génétique du développement des membres

Other titleThe genetic control of limb development
Published inAnnales de génétique, vol. 39, no. 4, p. 222-232
Publication date1996
Abstract

Vertebrate limbs are an amazing example of successful adaptation to various environmental conditions. In higher vertebrates forelimbs help to fly, swin, walk, dig, grasp or play the Passacaille, yet their basic structure (the sequence and spatial arrangement of bony elements) is always the same. This implies the existence of a unique developmental strategy for building a limb (a limb plan) that imposes early on a basic scheme, on the top of which subsequent species-specific customizations will occur. The description of such a universal limb plan, hence the idea that the genetic and developmental processses that generate this plan are very ancient, has been controversial for about a century. It is worth asking whether recent discoveries of important genes involved in these processes can bring novel arguments to the debate.

freeng
Keywords
  • Hox
  • Membre
  • Développement
  • Limb
  • Development
Citation (ISO format)
HERAULT, Yann, DUBOULE, Denis. Le contrôle génétique du développement des membres. In: Annales de génétique, 1996, vol. 39, n° 4, p. 222–232.
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Article (Published version)
accessLevelPublic
Identifiers
  • PID : unige:164913
ISSN of the journal0003-3995
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