Duboule, Denis | Archive ouverte UNIGE

Title	Published in	Year	Views	Downloads
Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos	Nature genetics	2023	93	50
Genetic cold cases: lessons from solving complex congenital limb disorders	Genes & development	2023	93	53
The (unusual) heuristic value of Hox gene clusters; a matter of time?	Developmental biology	2022	61	63
Context-dependent enhancer function revealed by targeted inter-TAD relocation	Nature communications	2022	261	181
Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken	Development	2022	98	42
Time‐sequenced transcriptomes of developing distal mouse limb buds: A comparative tissue layer analysis	Developmental dynamics	2021	108	97
Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations	Nature communications	2021	62	27
Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster	Genes & development	2021	61	47
Dbx2 regulation in limbs suggests inter tad sharing of enhancers	Developmental dynamics	2021	113	62
Induction of a chromatin boundary in vivo upon insertion of a TAD border	PLOS genetics	2021	59	28
Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae	Molecular biology and evolution	2021	122	270
A complex regulatory landscape involved in the development of mammalian external genitals	eLife	2020	60	30
The regulatory landscapes of developmental genes	Development	2020	129	906
Chromatin topology and the timing of enhancer function at the HoxD locus	Proceedings of the National Academy of Sciences of the United States of America	2020	82	43
Mammalian-specific ectodermal enhancers control the expression of hoxc genes in developing nails and hair follicles	Proceedings of the National Academy of Sciences of the United States of America	2020	93	31
The constrained architecture of mammalian Hox gene clusters	Proceedings of the National Academy of Sciences of the United States of America	2019	77	100
Tail Bud Progenitor Activity Relies on a Network Comprising Gdf11, Lin28, and Hox13 Genes	Developmental cell	2019	85	55
Characterization of paralogous uncx transcription factor encoding genes in zebrafish	Gene	2019	80	187
Commentary on paper by Leroy C. Stevens (1960)	Developmental biology	2019	56	27
Fryns type mesomelic dysplasia of the upper limbs caused by inverted duplications of the HOXD gene cluster	European journal of human genetics	2019	96	0
Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes	BMC biology	2019	69	35
Role of Hoxc genes in the development of the limb integumentary organ (nail, claw, or hoof)	The FASEB journal	2018	77	0
Rescue of an aggressive female sexual courtship in mice by CRISPR/Cas9 secondary mutation in vivo	BMC Research Notes	2018	316	107
Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids	Nature	2018	238	198
Response to Peron et al.	Genetics in medicine	2018	80	74
Noncoding copy-number variations are associated with congenital limb malformation	Genetics in medicine	2018	74	94
Similarities and differences in the regulation of HoxD genes during chick and mouse limb development	PLOS Biology	2018	488	317
Heterogeneous combinatorial expression of Hoxd genes in single cells during limb development	BMC Biology	2018	474	546
The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes	Genes & development	2017	70	70
Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr	Proceedings of the National Academy of Sciences of the United States of America	2017	69	79
Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock	Genes & development	2017	75	35
Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cells	Proceedings of the National Academy of Sciences	2017	412	216
Large scale genomic reorganization of topological domains at the HoxD locus	Genome biology	2017	58	45
Topological Domains, Metagenes, and the Emergence of Pleiotropic Regulations at Hox Loci	Current Topics in Developmental Biology	2016	56	0
A role for HOX13 proteins in the regulatory switch between TADs at the HoxD locus	Genes & development	2016	61	66
Hotair Is Dispensible for Mouse Development	PLOS genetics	2016	72	33
Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan	eLife	2016	57	54
Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape	Proceedings of the National Academy of Sciences	2016	409	404
Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model	Mechanisms of development	2015	64	115
Clustering of mammalian Hox genes with other H3K27me3 targets within an active nuclear domain	Proceedings of the National Academy of Sciences of the United States of America	2015	76	40
Structure, function and evolution of topologically associating domains (TADs) at HOX loci	FEBS letters	2015	49	0
Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states	Proceedings of the National Academy of Sciences of the United States of America	2015	56	109
Visualizing the HoxD Gene Cluster at the Nanoscale Level	Cold Spring Harbor Symposia on Quantitative Biology	2015	47	0
Conservation and Divergence of Regulatory Strategies at Hox Loci and the Origin of Tetrapod Digits	PLoS biology	2014	588	318
Evolving Hox Activity Profiles Govern Diversity in Locomotor Systems	Developmental cell	2014	58	0
Considerations when investigating lncrna function in vivo	eLife	2014	58	61
Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci	eLife	2014	60	39
Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci	Science	2014	56	0
Snakes: hatching of a model system for Evo-Devo?	The International journal of developmental biology	2014	59	161
SnapShot: Hox gene regulation	Cell	2014	349	0
Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs	Nature	2014	455	1
The Genetics of Murine Hox Loci: TAMERE, STRING, and PANTHERE to Engineer Chromosome Variants	Hox genes: methods and protocols	2014	52	0
Role of a polymorphism in a Hox/Pax-responsive enhancer in the evolution of the vertebrate spine	Proceedings of the National Academy of Sciences of the United States of America	2013	85	0
A switch between topological domains underlies HoxD genes collinearity in mouse limbs	Science	2013	406	1
Chromatin Architectures and Hox Gene Collinearity	Current Topics in Developmental Biology	2013	75	0
Chromatin organization and global regulation of Hox gene clusters	Philosophical transactions - Royal Society. Biological sciences	2013	67	151
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system	Proceedings of the National Academy of Sciences of the United States of America	2013	111	47
A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus	PLOS genetics	2013	89	87
Chromatin looping and organization at developmentally regulated gene loci	Wiley interdisciplinary reviews. Developmental biology	2013	59	27
Combined function of HoxA and HoxB clusters in neural crest cells	Developmental biology	2013	58	30
Multiple Enhancers Regulate Hoxd Genes and the Hotdog LncRNA during Cecum Budding	Cell reports	2013	61	35
Transgene- and locus-dependent imprinting reveals allele-specific chromosome conformations	Proceedings of the National Academy of Sciences of the United States of America	2013	56	103
Duplications of hox gene clusters and the emergence of vertebrates	Developmental biology	2013	92	44
Topology of mammalian developmental enhancers and their regulatory landscapes	Nature	2013	57	0
Des nageoires aux membres: l'apport de la génétique moléculaire du développement dans l'étude de l'évolution des morphologies chez les vertébrés	MS. Médecine sciences	2012	126	0
Structural and Functional Differences in the Long Non-Coding RNA Hotair in Mouse and Human	PLOS genetics	2011	535	281
A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig1 and Olig2 locus	PloS one	2010	865	490
Uncoupling Time and Space in the Collinear Regulation of Hox Genes	PLOS genetics	2009	477	459
Characterization of mouse Dactylaplasia mutations: a model for human ectrodactyly SHFM3	Mammalian genome	2008	718	443
Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development	PLOS genetics	2007	540	906
Un STRING lève le voile sur les mécanismes contrôlant l’expression des gènes Hox	MS. Médecine sciences	2006	78	0
Control of Hoxd genes' collinearity during early limb development	Developmental cell	2006	528	535
Head-tail patterning of the vertebrate embryo: one, two or many unresolved problems?	The International journal of developmental biology	2006	713	726
Colinearity Loops Out	Developmental cell	2004	478	206
An enhancer-titration effect induces digit-specific regulatory alleles of the HoxD cluster	Developmental biology	2003	511	0
A nested deletion approach to generate Cre deleter mice with progressive Hox profiles	The International journal of developmental biology	2002	467	123
Developmental Biology in Geneva: A Three Century-Long Tradition	The International journal of developmental biology	2002	134	990
The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator	Cell	2002	625	1
A t(2;8) balanced translocation with breakpoints near the human HOXD complex causes mesomelic dysplasia and vertebral defects	Genomics	2002	580	2
The mouse Hoxd13^spdh mutation, a polyalanine expansion similar to human type II synpolydactyly (SPD), disrupts the function but not the expression of other Hoxd genes	Developmental biology	2001	416	1
Targeted inversion of a polar silencer within the HoxD complex re-allocates domains of enhancer sharing	Nature genetics	2000	92	0
Mechanisms of Hox gene colinearity: transposition of the anterior Hoxb1 gene into the posterior HoxD complex	Genes & development	2000	466	1
No milk today (my Hox have gone away)	Proceedings of the National Academy of Sciences of the United States of America	1999	58	0
Hox Gene Expression in Limbs: Colinearity by Opposite Regulatory Controls	Developmental biology	1999	520	0
Hox genes in digit development and evolution	Cell and tissue research	1999	477	1
Breaking Colinearity in the Mouse HoxD Complex	Cell	1999	470	2
Classification of limb defects	American journal of medical genetics	1998	496	1
Hox is in the hair: a break in colinearity?	Genes & development	1998	520	1
Genetic control of murine limb morphogenesis: relationship with human syndromes and evolutionary relevance	Molecular and cellular endocrinology	1998	62	0
Control of Colinearity in AbdB Genes of the Mouse HoxD Complex	Molecular cell	1998	66	0
The evolution of 'bricolage'	Trends in genetics	1998	61	0
Engineering chromosomes in mice through targeted meiotic recombination (TAMERE)	Nature genetics	1998	78	0
Genetic analysis of a conserved sequence in the HoxD complex: regulatory redundancy or limitations of the transgenic approach?	Developmental dynamics	1998	528	418
Genetic analysis of a Hoxd-12 regulatory element reveals global versus local modes of controls in the HoxD complex	Development	1998	428	544
Vertebrate Hox gene regulation: clustering and/or colinearity?	Current opinion in genetics & development	1998	544	0
Les gènes Hox et le contrôle génétique de la fabrication des membres	Archives de pédiatrie	1997	509	1
Regulation of number and size of digits by posterior Hox genes: A dose-dependent mechanism with potential evolutionary implications	Proceedings of the National Academy of Sciences of the United States of America	1997	57	0
Ulnaless (Ul), a regulatory mutation inducing both loss-of-function and gain-of-function of posterior Hoxd genes	Development	1997	446	417
Le contrôle de la morphogenèse des membres par les gènes Hox	Comptes rendus des séances de la Société de biologie et de ses filiales	1997	176	119
Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum	EMBO journal	1997	524	1
Interspecies exchange of a Hoxd enhancer in vivo induces premature transcription and anterior shift of the sacrum	Developmental biology	1997	535	0
Dorso-ventral limb polarity and origin of the ridge: on the fringe of independence?	BioEssays	1997	564	1
Male accessory sex organ morphogenesis is altered by loss of function of Hoxd-13	Developmental dynamics	1997	572	371
Teleost HoxD and HoxA genes: comparison with tetrapods and functional evolution of the HOXD complex	Mechanisms of development	1996	80	0
Le contrôle génétique du développement des membres	Annales de génétique	1996	190	91
Transgenic analysis of a potential Hoxd-11 limb regulatory element present in tetrapods and fish	Developmental biology	1996	563	1
Zebrafish Hoxa and Evx-2 genes: cloning, developmental expression and implications for the functional evolution of posterior Hox genes	Mechanisms of development	1996	70	0
Function of the Evx-2 gene in the morphogenesis of vertebrate limbs	EMBO journal	1996	509	1
A molecular approach to the evolution of vertebrate paired appendages	Trends in ecology & evolution	1996	65	0
Gene Transpositions in the HoxD Complex Reveal a Hierarchy of Regulatory Controls	Cell	1996	462	1
Function of posterior HoxD genes in the morphogenesis of the anal sphincter	Development	1996	489	0
Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning	Developmental biology	1996	495	1
In vivo targeted mutagenesis of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundaries	Genes & development	1996	445	1
Colinearity and functional hierarchy among genes of the homeotic complexes	Trends in genetics	1994	64	0
Developmental expression of the mouse Evx-2 gene: relationship with the evolution of the HOM/Hox complex	Development	1994	464	173
Temporal colinearity and the phylotypic progression: a basis for the stability of a vertebrate Bauplan and the evolution of morphologies through heterochrony	Development	1994	465	487
The segment-specific gene Krox-20 encodes a transcription factor with binding sites in the promoter region of the Hox-1.4 gene	EMBO Journal	1990	457	0
DNA sequences homologous to the Drosophila opa repeat are present in murine mRNAs that are differentially expressed in fetuses and adult tissues	Molecular and Cellular Biology	1987	376	0
Hox-1.6: a mouse homeo-box-containing gene member of the Hox-1 complex	EMBO journal	1987	12	0
A new homeo-box is present in overlapping cosmid clones which define the mouse Hox-1 locus	EMBO Journal	1986	409	0