Scientific article
Open access

Two-component systems of S. aureus : signaling and sensing mechanisms

Published inGenes, vol. 13, no. 1, 34
Publication date2021-12-23
First online date2021-12-23

Staphylococcus aureus encodes 16 two-component systems (TCSs) that enable the bacteria to sense and respond to changing environmental conditions. Considering the function of these TCSs in bacterial survival and their potential role as drug targets, it is important to understand the exact mechanisms underlying signal perception. The differences between the sensing of appropriate signals and the transcriptional activation of the TCS system are often not well described, and the signaling mechanisms are only partially understood. Here, we review present insights into which signals are sensed by histidine kinases in S. aureus to promote appropriate gene expression in response to diverse environmental challenges.

  • S. aureus
  • Histidine kinase
  • Ligand
  • Signal sensing
  • Two-component systems
Citation (ISO format)
BLEUL, Lisa, FRANCOIS, Patrice, WOLZ, Christiane. Two-component systems of S. aureus : signaling and sensing mechanisms. In: Genes, 2021, vol. 13, n° 1, p. 34. doi: 10.3390/genes13010034
Main files (1)
Article (Published version)
ISSN of the journal2073-4425

Technical informations

Creation09/27/2022 8:53:00 AM
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