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Scientific article
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English

The Effect of Different Head Movement Paradigms on Vestibulo-Ocular Reflex Gain and Saccadic Eye Responses in the Suppression Head Impulse Test in Healthy Adult Volunteers

Published inFrontiers in neurology, vol. 12, 729081
Publication date2021
First online date2021-09-22
Abstract

Objective: This study aimed to identify differences in vestibulo-ocular reflex gain (VOR gain) and saccadic response in the suppression head impulse paradigm (SHIMP) between predictable and less predictable head movements, in a group of healthy subjects. It was hypothesized that higher prediction could lead to a lower VOR gain, a shorter saccadic latency, and higher grouping of saccades. Methods: Sixty-two healthy subjects were tested using the video head impulse test and SHIMPs in four conditions: active and passive head movements for both inward and outward directions. VOR gain, latency of the first saccade, and the level of saccade grouping (PR-score) were compared among conditions. Inward and active head movements were considered to be more predictable than outward and passive head movements. Results: After validation, results of 57 tested subjects were analyzed. Mean VOR gain was significantly lower for inward passive compared with outward passive head impulses (p < 0.001), and it was higher for active compared with passive head impulses (both inward and outward) (p ≤ 0.024). Mean latency of the first saccade was significantly shorter for inward active compared with inward passive (p ≤ 0.001) and for inward passive compared with outward passive head impulses (p = 0.012). Mean PR-score was only significantly higher in active outward than in active inward head impulses (p = 0.004). Conclusion: For SHIMP, a higher predictability in head movements lowered gain only in passive impulses and shortened latencies of compensatory saccades overall. For active impulses, gain calculation was affected by short-latency compensatory saccades, hindering reliable comparison with gains of passive impulses. Predictability did not substantially influence grouping of compensatory saccades.

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Keywords
  • Active head impulse
  • Inward head impulse
  • Outward head impulse
  • Passive head impulse
  • Suppression head impulse paradigm
  • Vestibular ocular reflex
  • Video head impulse test (vHIT)
Citation (ISO format)
STARKOV, Dmitrii et al. The Effect of Different Head Movement Paradigms on Vestibulo-Ocular Reflex Gain and Saccadic Eye Responses in the Suppression Head Impulse Test in Healthy Adult Volunteers. In: Frontiers in neurology, 2021, vol. 12, p. 729081. doi: 10.3389/fneur.2021.729081
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Identifiers
ISSN of the journal1664-2295
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Technical informations

Creation11/04/2021 3:38:00 PM
First validation11/04/2021 3:38:00 PM
Update time03/16/2023 2:34:11 AM
Status update03/16/2023 2:34:08 AM
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