Scientific article
Open access

Decrease in pain perception during acute SARS-CoV-2 infection: a case series

Other titleDecrease in pain perception during acute severe acute respiratory syndrome coronavirus 2 infection: a case series
Published inPain
First online date2021-10-11

Many reports have described pain appearance or an increase of chronic pain concomitant to SARS-CoV-2 infection. Here, we describe the cases of three patients with chronic cancer pain, in which COVID-19 was associated with a dramatic reduction/disappearance of pain. Pain reappeared following recovery from COVID-19. Neurological imaging and pathological findings, when available, were inconclusive. To our knowledge, this is the first case series reporting an acute reduction in pain perception in COVID-19. We believe further investigation is mandatory, as it could shed new light on the mechanisms of pain perception and modulation.

  • COVID-19
  • SARS-CoV-2
  • Pain
  • Palliative care
  • Oncology
  • Silent hypoxemia
Citation (ISO format)
HENTSCH, Lisa et al. Decrease in pain perception during acute SARS-CoV-2 infection: a case series. In: Pain, 2021. doi: 10.1097/j.pain.0000000000002512
Main files (2)
Article (Published version)
Article (Accepted version)
ISSN of the journal0304-3959

Technical informations

Creation10/18/2021 11:12:00 AM
First validation10/18/2021 11:12:00 AM
Update time03/16/2023 2:25:07 AM
Status update03/16/2023 2:25:06 AM
Last indexation05/06/2024 8:54:45 AM
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