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Title

Experimental cerebral palsy causes microstructural brain damage in areas associated to motor deficits but no spatial memory impairments in the developing rat
Authors
Sanchez, Oliver Lope
Carvalho, A S
Van De Looij, Yohan
Toulotte, A
Wyse, A T
Netto, C A
Sizonenko, Stéphane
Published in Brain Research. 2021, vol. 1761, 147389
Abstract Cerebral palsy (CP) is the major cause of motor and cognitive impairments during childhood. CP can result from direct or indirect structural injury to the developing brain. In this study, we aimed to describe brain damage and behavioural alterations during early adult life in a CP model using the combination of maternal inflammation, perinatal anoxia and postnatal sensorimotor restriction.
Keywords Cerebral palsy — Inflammation — Anoxia — Sensorimotor restriction — Brain damage — Diffusion Tensor Imaging
Identifiers
PMID: 33639200
Full text
Article (Published version) (3.9 MB) - document accessible for UNIGE members only Limited access to UNIGE
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Other version: https://www.sciencedirect.com/science/article/pii/S0006899321001141
Structures
Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique
Research group L'imagerie cérébrale (184)
Citation
(ISO format) 		SANCHEZ, Oliver Lope et al. Experimental cerebral palsy causes microstructural brain damage in areas associated to motor deficits but no spatial memory impairments in the developing rat. In: Brain Research, 2021, vol. 1761, p. 147389. doi: 10.1016/j.brainres.2021.147389 https://archive-ouverte.unige.ch/unige:157744

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Deposited on : 2022-01-07

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