Scientific article

English

Cohort profile: SCREEN-RA: design, methods and perspectives of a Swiss cohort study of first-degree relatives of patients with rheumatoid arthritis

ContributorsGilbert, Benoît Thomas P.

; Lamacchia, Céline; Mongin, Denis

; Trunk, Eric; Studer, Olivia; Courvoisier, Delphine

; Rubbert-Roth, Andrea; Kyburz, Diego; Moeller, Burkhard; Finckh, Axel

Published inBMJ Open, vol. 11, no. 7, e048409

Publication date2021

Abstract

Rheumatoid arthritis (RA) is an insidious autoimmune disease, with an immunological onset years before diagnosis. Early interventions in preclinical stages could prevent or minimise the progression towards irreversible joint damage. The SCREEN-RA cohort (Evaluation of a SCREENing strategy for Rheumatoid Arthritis) aims to characterise the preclinical stages of the disease, to identify environmental risk factors, and to discover or validate novel biomarkers predictive for RA development.

Keywords

Adult
Arthritis, Rheumatoid/diagnosis/genetics
Autoantibodies
Cohort Studies
Ethnic Groups
Female
Humans
Male
Switzerland/epidemiology

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Funding

Autre - Swiss National Science Foundation, the Schmidheiny Foundation, and DeReuter Foundation

Citation (ISO format)

GILBERT, Benoît Thomas P. et al. Cohort profile: SCREEN-RA: design, methods and perspectives of a Swiss cohort study of first-degree relatives of patients with rheumatoid arthritis. In: BMJ Open, 2021, vol. 11, n° 7, p. e048409. doi: 10.1136/bmjopen-2020-048409

Article (Published version)

Identifiers

PID : unige:157598
DOI : 10.1136/bmjopen-2020-048409
PMID : 34261688

Additional URL for this publicationhttps://bmjopen.bmj.com/content/11/7/e048409

Journal ISSN2044-6055

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Creation16/08/2021 13:29:00

First validation16/08/2021 13:29:00

Update time16/03/2023 02:14:17

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