Risk of reinfection after seroconversion to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): A population-based propensity-score matched cohort study

Leidi, Antonio Siro Gabriele; Koegler, Flora Anaïd; Dumont, Roxane; Dubos, Richard; Zaballa, María-Eugenia; Piumatti, Giovanni; Coen, Matteo; Berner, Amandine; Darbellay, Pauline; Vetter, Pauline; Vuilleumier, Nicolas; Kaiser, Laurent; Courvoisier, Delphine; Azman, Andrew; Guessous, Idris; Stringhini, Silvia; SEROCoV-POP study group

doi:10.1093/cid/ciab495

Scientific article

English

Risk of reinfection after seroconversion to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): A population-based propensity-score matched cohort study

Published inClinical Infectious Diseases

Publication date2021

Abstract

Serological assays detecting anti-SARS-CoV-2 antibodies are being widely deployed in studies and clinical practice. However, the duration and effectiveness of the protection conferred by the immune response remains to be assessed in population-based samples. To estimate the incidence of newly acquired SARS-CoV-2 infections in seropositive individuals as compared to seronegative controls we conducted a retrospective longitudinal matched study.

Keywords

SARS-CoV-2
Reinfection
COVID-19
Antibody
Protection

Affiliation entities

Research groups

Citation (ISO format)

LEIDI, Antonio Siro Gabriele et al. Risk of reinfection after seroconversion to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): A population-based propensity-score matched cohort study. In: Clinical Infectious Diseases, 2021. doi: 10.1093/cid/ciab495