en
Scientific article
Open access
English

Cerebrospinal Fluid Features in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reverse Transcription Polymerase Chain Reaction (RT-PCR) Positive Patients

Published inClinical infectious diseases, vol. 73, no. 9, p. e3102-e3105
Publication date2021-11-01
First online date2020-08-08
Abstract

This study analyzed the cerebrospinal fluid features of 31 coronavirus disease 2019 (COVID-19) patients with neurological complications. We observed neither severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in the cerebrospinal fluid, nor intrathecal immunoglobulin G (IgG) synthesis but did observe signs of blood-brain barrier disruption. These results might serve as a basis for a better understanding of SARS-CoV-2 related neuropathogenesis.

eng
Keywords
  • COVID-19
  • SARS-CoV-2
  • Blood-brain barrier
  • Intrathecal synthesis
  • Neurological manifestations
Citation (ISO format)
BELLON, Mathilde Anne et al. Cerebrospinal Fluid Features in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reverse Transcription Polymerase Chain Reaction (RT-PCR) Positive Patients. In: Clinical infectious diseases, 2021, vol. 73, n° 9, p. e3102–e3105. doi: 10.1093/cid/ciaa1165
Main files (1)
Article (Published version)
Secondary files (1)
Identifiers
ISSN of the journal1058-4838
140views
52downloads

Technical informations

Creation11/03/2021 9:57:00 AM
First validation11/03/2021 9:57:00 AM
Update time03/16/2023 1:42:20 AM
Status update03/16/2023 1:42:19 AM
Last indexation02/12/2024 1:32:04 PM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack