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Scientific article
Review
English

Midline cells and the organization of the vertebrate neuraxis

Published inCurrent Opinion in Genetics & Development, vol. 3, no. 4, p. 633-640
Publication date1993
Abstract

Vertebrate embryos exhibit a striking midline axis of symmetry that can be recognized in the overall body plan, the framework of skeletal structures and the organization of the nervous system. Cells located at the midline of the embryo during gastrulation have a crucial influence on the establishment of cell identity and pattern within the nervous system. The identification of transcription factors and secreted proteins that are expressed by these midline cell groups has begun to provide a molecular characterization of the organizing centers that establish early neural identity and pattern.

Keywords
  • Animals
  • Embryonic and Fetal Development
  • Nervous System/embryology
  • Signal Transduction
  • Vertebrates/embryology
Affiliation Not a UNIGE publication
Citation (ISO format)
RUIZ ALTABA, Ariel, JESSELL, T M. Midline cells and the organization of the vertebrate neuraxis. In: Current Opinion in Genetics & Development, 1993, vol. 3, n° 4, p. 633–640. doi: 10.1016/0959-437x(93)90100-4
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ISSN of the journal0959-437X
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