Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos

Ruiz Altaba, Ariel; Melton, D A

doi:10.1038/341033a0

Scientific article

English

Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos

Contributors

Ruiz Altaba, Ariel; Melton, D A

Published in

Nature, vol. 341, no. 6237, p. 33-38

Publication date

1989

Abstract

The expression of the Xenopus homoeobox gene xhox3 is an early response to mesoderm induction by peptide growth factors and the level of xhox3 expression marks the antero-posterior character of the induced mesoderm. Different peptide growth factors specify different antero-posterior mesodermal cell fates as seen by the level of xhox3 expression and the capacity to induce specific secondary neural/epidermal structures. These factors and homoeobox genes thus form part of the mechanism necessary for establishing antero-posterior polarity in the frog embryo.

Keywords

Animals
Cell Differentiation
Embryonic Induction
Gene Expression Regulation
Genes
Homeobox
Growth Substances/physiology
Mesoderm/physiology
Morphogenesis
RNA
Messenger/genetics
Xenopus laevis/embryology

UNIGE affiliation entities

Not a UNIGE publication

UNIGE research groups

Stemness dans le développement et les maladies: Signalisation, reprogrammation et mécanismes des métastases (776)

Citation (ISO format)

RUIZ ALTABA, Ariel, MELTON, D A. Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos. In: Nature, 1989, vol. 341, n° 6237, p. 33–38. doi: 10.1038/341033a0

Article (Published version)

Identifiers

PID : unige:154191
DOI : 10.1038/341033a0
PMID : 2570357

Journal ISSN

0028-0836

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Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos

Contributors

Published in

Publication date

Abstract

Keywords

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

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Journal ISSN

Technical informations

Creation

First validation

Update

Status update

Last indexation