The impact of seropositivity on the effectiveness of biologic anti-rheumatic agents: results from a collaboration of 16 registries

Courvoisier, Delphine; Chatzidionysiou, Katarina; Mongin, Denis; Lauper, Kim; Mariette, Xavier; Morel, Jacques; Gottenberg, Jacques-Eric; Bergstra, Sytske Anne; Suarez, Manuel Pombo; Codreanu, Catalin; Kvien, Tore K; Santos, Maria Jose; Pavelka, Karel; Hetland, Merete L; Askling, Johan; Turesson, Carl; Kubo, Satoshi; Tanaka, Yoshiya; Iannone, Florenzo; Choquette, Denis; Nordström, Dan C; Rotar, Ziga; Lukina, Galina; Gabay, Cem; Van Vollenhoven, Ronald; Finckh, Axel

doi:10.1093/rheumatology/keaa393

Scientific article

English

The impact of seropositivity on the effectiveness of biologic anti-rheumatic agents: results from a collaboration of 16 registries

Published inRheumatology, vol. 60, no. 2, p. 820-828

Publication date2021

Abstract

RF and ACPA are used as diagnostic tools and their presence has been associated with clinical response to some biologic DMARDs (bDMARDs) in RA. This study compared the impact of seropositivity on drug discontinuation and effectiveness of bDMARDs in patients with RA, using head-to-head comparisons in a real-world setting.

Keywords

ACPA
PANABA
TOCERRA
Anti-citrullinated protein antibodies
Drug retention
Rheumatoid arthritis
Rheumatoid factor
Seropositivity

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Citation (ISO format)

COURVOISIER, Delphine et al. The impact of seropositivity on the effectiveness of biologic anti-rheumatic agents: results from a collaboration of 16 registries. In: Rheumatology, 2021, vol. 60, n° 2, p. 820–828. doi: 10.1093/rheumatology/keaa393

Article (Published version)

Supplemental data

Identifiers

PID : unige:152634
DOI : 10.1093/rheumatology/keaa393
PMID : 32810263

Additional URL for this publicationhttps://academic.oup.com/rheumatology/article/60/2/820/5894051

Journal ISSN1462-0324

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Creation23/03/2021 14:47:00

First validation23/03/2021 14:47:00

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The impact of seropositivity on the effectiveness of biologic anti-rheumatic agents: results from a collaboration of 16 registries

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