The Target Of Rapamycin (TOR) kinase functions in two unique protein complexes, named TORC1 and TORC2. TORC1 and TORC2 differ in terms of their structure and localization, but they also present some similarities including the upstream stimuli they sense; i.e. both complexes appear to respond to changes in glucose levels. We found that TORC2 senses glucose in a manner that is at least partially distinct from the glucose signalling that is upstream of TORC1 which involves the SEA and EGO complexes. In contrast, our results demonstrate that the first step in glucose signalling to TORC2 requires any of the three yeast hexokinases bound to their substrate. We genetically uncoupled the catalytic and signalling function of hexokinases, further supporting the role of these glycolytic enzymes in glucose signalling per se. Interestingly, we found that this signalling pathway acts in parallel to inversely regulate the yeast AMPK - Snf1.