RL
Loewith, Robbie Joséph
| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain | Nature |  | 2024 | 115 | 19 | ||
| Small Molecule Modulator of the mTORC2 Pathway Discovered from a DEL Library Designed to Bind to Pleckstrin Homology Domains | ACS chemical biology | | 2024 | 10 | 14 | ||
| Dynamic metabolome profiling uncovers potential TOR signaling genes | eLife | | 2023 | 188 | 125 | ||
| EGOC inhibits TOROID polymerization by structurally activating TORC1 | Nature structural & molecular biology | | 2023 | 79 | 72 | ||
| Cryo-EM structure of the SEA complex | Nature | | 2022 | 199 | 59 | ||
| Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast | Journal of cell science | | 2022 | 148 | 174 | ||
| Passive coupling of membrane tension and cell volume during active response of cells to osmosis | Proceedings of the National Academy of Sciences of the United States of America | | 2021 | 402 | 171 | ||
| Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides | ACS Central Science | | 2021 | 328 | 147 | ||
| Flipper Probes for the Community | Chimia | | 2021 | 406 | 129 | ||
| Chemical-Biology-derived in vivo Sensors: Past, Present, and Future | Chimia | | 2021 | 122 | 96 | ||
| The flipside of the TOR coin – TORC2 and plasma membrane homeostasis at a glance | Journal of cell science | | 2020 | 181 | 208 | ||
| TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast | The Journal of biological chemistry | | 2020 | 192 | 70 | ||
| Phosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55 | Proteomics |  | 2020 | 146 | 0 | ||
| Resolving the Communication GAPs Upstream of TORC1 | Developmental cell | | 2020 | 180 | 160 | ||
| Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9 | Molecular and Cellular Proteomics | | 2020 | 444 | 266 | ||
| Structural Insights into TOR Signaling | Genes | | 2020 | 406 | 63 | ||
| The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast | Molecular Cell | | 2020 | 362 | 1 | ||
| TOR Signaling Is Going through a Phase | Cell metabolism | | 2019 | 108 | 37 | ||
| TORC2 controls endocytosis through plasma membrane tension | The Journal of Cell Biology | | 2019 | 566 | 141 | ||
| Sphingolipids and membrane targets for therapeutics | Current Opinion in Chemical Biology | | 2019 | 512 | 3 | ||
| Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity | Developmental cell | | 2019 | 218 | 102 | ||
| Target of rapamycin complex 2–dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae | The Journal of biological chemistry | | 2018 | 87 | 70 | ||
| Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2 | Nature Cell Biology | | 2018 | 570 | 2 | ||
| Regulation of Cellular Metabolism through Phase Separation of Enzymes | Biomolecules | | 2018 | 325 | 228 | ||
| Systematic analysis of complex genetic interactions | Science | | 2018 | 202 | 271 | ||
| Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2 | Nature Communications | | 2017 | 472 | 207 | ||
| TORC1 organized in inhibited domains (TOROIDs) regulate TORC1 activity | Nature | | 2017 | 480 | 0 | ||
| Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation | Journal of Biological Chemistry | | 2017 | 492 | 194 | ||
| A pathway of targeted autophagy is induced by DNA damage in budding yeast | Proceedings of the National Academy of Sciences | | 2017 | 471 | 219 | ||
| Tensing Up for Lipid Droplet Formation | Developmental Cell | | 2017 | 419 | 0 | ||
| TOR Complexes and the Maintenance of Cellular Homeostasis | Trends in Cell Biology | | 2016 | 478 | 0 | ||
| TORC2 Structure and Function | Trends in Biochemical Sciences | | 2016 | 525 | 2 | ||
| Dual action antifungal small molecule modulates multidrug efflux and TOR signaling | Nature chemical biology | | 2016 | 566 | 0 | ||
| A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction | Scientific Reports | | 2016 | 492 | 188 | ||
| TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae | Molecular Biology of the Cell | | 2016 | 459 | 214 | ||
| Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2 | Molecular Cell | | 2015 | 461 | 0 | ||
| Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways | Journal of Biological Chemistry | | 2015 | 472 | 187 | ||
| A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast | PLOS Genetics | | 2014 | 460 | 144 | ||
| Roles for PI(3,5)P2 in nutrient sensing through TORC1 | Molecular Biology of the Cell | | 2014 | 474 | 159 | ||
| Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis | Molecular Biology of the Cell | | 2014 | 541 | 254 | ||
| TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks | Molecular Cell | | 2013 | 443 | 0 | ||
| Growth control: function follows form | Current Biology | | 2013 | 432 | 151 | ||
| Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis | Nature cell biology | | 2012 | 1,047 | 2 | ||
| Amino acid signaling in high definition | Structure | | 2012 | 757 | 0 | ||
| Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry | ACS chemical biology | | 2012 | 611 | 1 | ||
| Chemical Biology Approaches to Membrane Homeostasis and Function | Chimia | | 2011 | 769 | 64 | ||
| Target of rapamycin (TOR) in nutrient signaling and growth control | Genetics | | 2011 | 629 | 3 | ||
| Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L | EMBO journal | | 2011 | 683 | 464 | ||
| Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae | Eukaryotic cell | | 2011 | 611 | 278 | ||
| A brief history of TOR | Biochemical Society transactions | | 2011 | 568 | 684 | ||
| Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast | Science signaling | | 2010 | 715 | 791 | ||
| Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology | Molecular biology of the cell | | 2009 | 717 | 530 | ||
| Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis | Genes & development | | 2009 | 679 | 676 | ||
| The Vam6 GEF controls TORC1 by activating the EGO complex | Molecular cell | | 2009 | 634 | 458 | ||
| Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling | Molecular cell | | 2009 | 637 | 394 | ||
| Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response | Molecular biology of the cell | | 2009 | 698 | 750 | ||
| Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 | PLoS biology | | 2009 | 718 | 497 | ||
| Caffeine extends yeast lifespan by targeting TORC1 | Molecular microbiology | | 2008 | 608 | 699 | ||
| Mutual antagonism of target of rapamycin and calcineurin signaling | The Journal of biological chemistry | | 2006 | 140 | 38 | ||
| The TOR signalling network from yeast to man | International journal of biochemistry & cell biology | | 2006 | 578 | 604 | ||
| TOR signaling in growth and metabolism | Cell | | 2006 | 922 | 1,477 | ||
| A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling | Cell | | 2006 | 645 | 1,079 | ||
| Cell growth control: little eukaryotes make big contributions | Oncogene | | 2006 | 637 | 2,426 |
