RL
Loewith, Robbie Joséph
Affiliation entities
Research groups
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain | Nature | 2024 | 5 | 5 | |||
Dynamic metabolome profiling uncovers potential TOR signaling genes | eLife | 2023 | 133 | 83 | |||
EGOC inhibits TOROID polymerization by structurally activating TORC1 | Nature structural & molecular biology | 2023 | 38 | 38 | |||
Cryo-EM structure of the SEA complex | Nature | 2022 | 159 | 44 | |||
Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast | Journal of cell science | 2022 | 113 | 109 | |||
Passive coupling of membrane tension and cell volume during active response of cells to osmosis | Proceedings of the National Academy of Sciences of the United States of America | 2021 | 336 | 93 | |||
Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides | ACS Central Science | 2021 | 288 | 137 | |||
Flipper Probes for the Community | Chimia | 2021 | 328 | 75 | |||
Chemical-Biology-derived in vivo Sensors: Past, Present, and Future | Chimia | 2021 | 85 | 63 | |||
The flipside of the TOR coin – TORC2 and plasma membrane homeostasis at a glance | Journal of cell science | 2020 | 155 | 132 | |||
TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast | The Journal of biological chemistry | 2020 | 146 | 58 | |||
Phosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55 | Proteomics | 2020 | 105 | 0 | |||
Resolving the Communication GAPs Upstream of TORC1 | Developmental cell | 2020 | 134 | 113 | |||
Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9 | Molecular and Cellular Proteomics | 2020 | 395 | 249 | |||
Structural Insights into TOR Signaling | Genes | 2020 | 369 | 51 | |||
The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast | Molecular Cell | 2020 | 331 | 1 | |||
TOR Signaling Is Going through a Phase | Cell metabolism | 2019 | 84 | 18 | |||
TORC2 controls endocytosis through plasma membrane tension | The Journal of Cell Biology | 2019 | 499 | 129 | |||
Sphingolipids and membrane targets for therapeutics | Current Opinion in Chemical Biology | 2019 | 461 | 3 | |||
Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity | Developmental cell | 2019 | 166 | 53 | |||
Target of rapamycin complex 2–dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae | The Journal of biological chemistry | 2018 | 47 | 53 | |||
Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2 | Nature Cell Biology | 2018 | 516 | 2 | |||
Regulation of Cellular Metabolism through Phase Separation of Enzymes | Biomolecules | 2018 | 293 | 177 | |||
Systematic analysis of complex genetic interactions | Science | 2018 | 146 | 169 | |||
Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2 | Nature Communications | 2017 | 429 | 195 | |||
TORC1 organized in inhibited domains (TOROIDs) regulate TORC1 activity | Nature | 2017 | 440 | 0 | |||
Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation | Journal of Biological Chemistry | 2017 | 429 | 164 | |||
A pathway of targeted autophagy is induced by DNA damage in budding yeast | Proceedings of the National Academy of Sciences | 2017 | 411 | 194 | |||
Tensing Up for Lipid Droplet Formation | Developmental Cell | 2017 | 368 | 0 | |||
TOR Complexes and the Maintenance of Cellular Homeostasis | Trends in Cell Biology | 2016 | 414 | 0 | |||
TORC2 Structure and Function | Trends in Biochemical Sciences | 2016 | 470 | 2 | |||
Dual action antifungal small molecule modulates multidrug efflux and TOR signaling | Nature chemical biology | 2016 | 529 | 0 | |||
A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction | Scientific Reports | 2016 | 449 | 169 | |||
TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae | Molecular Biology of the Cell | 2016 | 425 | 203 | |||
Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2 | Molecular Cell | 2015 | 426 | 0 | |||
Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways | Journal of Biological Chemistry | 2015 | 433 | 168 | |||
A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast | PLOS Genetics | 2014 | 421 | 128 | |||
Roles for PI(3,5)P2 in nutrient sensing through TORC1 | Molecular Biology of the Cell | 2014 | 434 | 147 | |||
Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis | Molecular Biology of the Cell | 2014 | 502 | 240 | |||
TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks | Molecular Cell | 2013 | 392 | 0 | |||
Growth control: function follows form | Current Biology | 2013 | 409 | 142 | |||
Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis | Nature cell biology | 2012 | 1 013 | 2 | |||
Amino acid signaling in high definition | Structure | 2012 | 737 | 0 | |||
Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry | ACS chemical biology | 2012 | 574 | 1 | |||
Chemical Biology Approaches to Membrane Homeostasis and Function | Chimia | 2011 | 691 | 55 | |||
Target of rapamycin (TOR) in nutrient signaling and growth control | Genetics | 2011 | 583 | 3 | |||
Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L | EMBO journal | 2011 | 642 | 445 | |||
Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae | Eukaryotic cell | 2011 | 589 | 273 | |||
A brief history of TOR | Biochemical Society transactions | 2011 | 529 | 639 | |||
Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast | Science signaling | 2010 | 668 | 714 | |||
Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology | Molecular biology of the cell | 2009 | 655 | 481 | |||
Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis | Genes & development | 2009 | 643 | 628 | |||
The Vam6 GEF controls TORC1 by activating the EGO complex | Molecular cell | 2009 | 587 | 430 | |||
Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling | Molecular cell | 2009 | 603 | 366 | |||
Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response | Molecular biology of the cell | 2009 | 643 | 719 | |||
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 | PLoS biology | 2009 | 658 | 471 | |||
Caffeine extends yeast lifespan by targeting TORC1 | Molecular microbiology | 2008 | 571 | 632 | |||
Mutual antagonism of target of rapamycin and calcineurin signaling | The Journal of biological chemistry | 2006 | 106 | 19 | |||
The TOR signalling network from yeast to man | International journal of biochemistry & cell biology | 2006 | 526 | 550 | |||
TOR signaling in growth and metabolism | Cell | 2006 | 815 | 1 243 | |||
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling | Cell | 2006 | 604 | 1 044 | |||
Cell growth control: little eukaryotes make big contributions | Oncogene | 2006 | 584 | 2 350 |