RL
Loewith, Robbie Joséph
| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain | Nature |  | 2024 | 86 | 15 | ||
| Small Molecule Modulator of the mTORC2 Pathway Discovered from a DEL Library Designed to Bind to Pleckstrin Homology Domains | ACS chemical biology | | 2024 | 3 | 6 | ||
| Dynamic metabolome profiling uncovers potential TOR signaling genes | eLife | | 2023 | 165 | 117 | ||
| EGOC inhibits TOROID polymerization by structurally activating TORC1 | Nature structural & molecular biology | | 2023 | 60 | 56 | ||
| Cryo-EM structure of the SEA complex | Nature | | 2022 | 187 | 56 | ||
| Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast | Journal of cell science | | 2022 | 138 | 139 | ||
| Passive coupling of membrane tension and cell volume during active response of cells to osmosis | Proceedings of the National Academy of Sciences of the United States of America | | 2021 | 368 | 133 | ||
| Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides | ACS Central Science | | 2021 | 307 | 144 | ||
| Flipper Probes for the Community | Chimia | | 2021 | 377 | 107 | ||
| Chemical-Biology-derived in vivo Sensors: Past, Present, and Future | Chimia | | 2021 | 113 | 86 | ||
| The flipside of the TOR coin – TORC2 and plasma membrane homeostasis at a glance | Journal of cell science | | 2020 | 172 | 173 | ||
| TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast | The Journal of biological chemistry | | 2020 | 175 | 67 | ||
| Phosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55 | Proteomics |  | 2020 | 136 | 0 | ||
| Resolving the Communication GAPs Upstream of TORC1 | Developmental cell | | 2020 | 169 | 149 | ||
| Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9 | Molecular and Cellular Proteomics | | 2020 | 427 | 263 | ||
| Structural Insights into TOR Signaling | Genes | | 2020 | 395 | 58 | ||
| The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast | Molecular Cell | | 2020 | 350 | 1 | ||
| TOR Signaling Is Going through a Phase | Cell metabolism | | 2019 | 97 | 31 | ||
| TORC2 controls endocytosis through plasma membrane tension | The Journal of Cell Biology | | 2019 | 543 | 138 | ||
| Sphingolipids and membrane targets for therapeutics | Current Opinion in Chemical Biology | | 2019 | 490 | 3 | ||
| Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity | Developmental cell | | 2019 | 191 | 80 | ||
| Target of rapamycin complex 2–dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae | The Journal of biological chemistry | | 2018 | 67 | 64 | ||
| Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2 | Nature Cell Biology | | 2018 | 545 | 2 | ||
| Regulation of Cellular Metabolism through Phase Separation of Enzymes | Biomolecules | | 2018 | 318 | 216 | ||
| Systematic analysis of complex genetic interactions | Science | | 2018 | 181 | 236 | ||
| Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2 | Nature Communications | | 2017 | 456 | 202 | ||
| TORC1 organized in inhibited domains (TOROIDs) regulate TORC1 activity | Nature | | 2017 | 473 | 0 | ||
| Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation | Journal of Biological Chemistry | | 2017 | 464 | 184 | ||
| A pathway of targeted autophagy is induced by DNA damage in budding yeast | Proceedings of the National Academy of Sciences | | 2017 | 451 | 210 | ||
| Tensing Up for Lipid Droplet Formation | Developmental Cell | | 2017 | 402 | 0 | ||
| TOR Complexes and the Maintenance of Cellular Homeostasis | Trends in Cell Biology | | 2016 | 447 | 0 | ||
| TORC2 Structure and Function | Trends in Biochemical Sciences | | 2016 | 513 | 2 | ||
| Dual action antifungal small molecule modulates multidrug efflux and TOR signaling | Nature chemical biology | | 2016 | 549 | 0 | ||
| A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction | Scientific Reports | | 2016 | 478 | 171 | ||
| TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae | Molecular Biology of the Cell | | 2016 | 444 | 210 | ||
| Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2 | Molecular Cell | | 2015 | 454 | 0 | ||
| Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways | Journal of Biological Chemistry | | 2015 | 447 | 175 | ||
| A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast | PLOS Genetics | | 2014 | 450 | 135 | ||
| Roles for PI(3,5)P2 in nutrient sensing through TORC1 | Molecular Biology of the Cell | | 2014 | 465 | 157 | ||
| Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis | Molecular Biology of the Cell | | 2014 | 533 | 250 | ||
| TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks | Molecular Cell | | 2013 | 425 | 0 | ||
| Growth control: function follows form | Current Biology | | 2013 | 423 | 145 | ||
| Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis | Nature cell biology | | 2012 | 1,041 | 2 | ||
| Amino acid signaling in high definition | Structure | | 2012 | 748 | 0 | ||
| Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry | ACS chemical biology | | 2012 | 597 | 1 | ||
| Chemical Biology Approaches to Membrane Homeostasis and Function | Chimia | | 2011 | 750 | 60 | ||
| Target of rapamycin (TOR) in nutrient signaling and growth control | Genetics | | 2011 | 614 | 3 | ||
| Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L | EMBO journal | | 2011 | 671 | 453 | ||
| Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae | Eukaryotic cell | | 2011 | 604 | 275 | ||
| A brief history of TOR | Biochemical Society transactions | | 2011 | 555 | 660 | ||
| Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast | Science signaling | | 2010 | 698 | 772 | ||
| Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology | Molecular biology of the cell | | 2009 | 686 | 519 | ||
| Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis | Genes & development | | 2009 | 663 | 659 | ||
| The Vam6 GEF controls TORC1 by activating the EGO complex | Molecular cell | | 2009 | 618 | 445 | ||
| Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling | Molecular cell | | 2009 | 626 | 387 | ||
| Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response | Molecular biology of the cell | | 2009 | 679 | 746 | ||
| Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 | PLoS biology | | 2009 | 699 | 486 | ||
| Caffeine extends yeast lifespan by targeting TORC1 | Molecular microbiology | | 2008 | 598 | 671 | ||
| Mutual antagonism of target of rapamycin and calcineurin signaling | The Journal of biological chemistry | | 2006 | 126 | 33 | ||
| The TOR signalling network from yeast to man | International journal of biochemistry & cell biology | | 2006 | 564 | 586 | ||
| TOR signaling in growth and metabolism | Cell | | 2006 | 887 | 1,415 | ||
| A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling | Cell | | 2006 | 631 | 1,065 | ||
| Cell growth control: little eukaryotes make big contributions | Oncogene | | 2006 | 619 | 2,393 |
