RL
Loewith, Robbie Joséph
| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| Limited proteolysis-coupled mass spectrometry captures proteome-wide protein structural alterations and biomolecular condensation in living cells | Molecular systems biology |  | 2026 | 4 | 59 | ||
| Structure and function of the yeast amino acid-sensing SEAC–EGOC supercomplex | Nature structural & molecular biology | | 2026 | 5 | 53 | ||
| TOR signaling on membranes | FEBS letters |  | 2025 | 5 | 0 | ||
| A dynamic feedback loop between retrograde sterol transport and TORC2 controls adaptation of the plasma membrane to stress | EMBO journal | | 2025 | 17 | 13 | ||
| Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain | Nature | | 2024 | 169 | 42 | ||
| Small Molecule Modulator of the mTORC2 Pathway Discovered from a DEL Library Designed to Bind to Pleckstrin Homology Domains | ACS chemical biology | | 2024 | 26 | 48 | ||
| Dynamic metabolome profiling uncovers potential TOR signaling genes | eLife | | 2023 | 213 | 227 | ||
| EGOC inhibits TOROID polymerization by structurally activating TORC1 | Nature structural & molecular biology | | 2023 | 111 | 160 | ||
| Cryo-EM structure of the SEA complex | Nature | | 2022 | 234 | 146 | ||
| Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast | Journal of cell science | | 2022 | 175 | 499 | ||
| Passive coupling of membrane tension and cell volume during active response of cells to osmosis | Proceedings of the National Academy of Sciences of the United States of America | | 2021 | 439 | 291 | ||
| Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides | ACS Central Science | | 2021 | 358 | 530 | ||
| Flipper Probes for the Community | Chimia | | 2021 | 468 | 304 | ||
| Chemical-Biology-derived in vivo Sensors: Past, Present, and Future | Chimia | | 2021 | 152 | 265 | ||
| The flipside of the TOR coin – TORC2 and plasma membrane homeostasis at a glance | Journal of cell science | | 2020 | 202 | 506 | ||
| TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast | The Journal of biological chemistry | | 2020 | 235 | 194 | ||
| Phosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55 | Proteomics | | 2020 | 176 | 0 | ||
| Resolving the Communication GAPs Upstream of TORC1 | Developmental cell | | 2020 | 221 | 208 | ||
| Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9 | Molecular and Cellular Proteomics | | 2020 | 485 | 283 | ||
| Structural Insights into TOR Signaling | Genes | | 2020 | 428 | 108 | ||
| The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast | Molecular Cell | | 2020 | 391 | 1 | ||
| TOR Signaling Is Going through a Phase | Cell metabolism | | 2019 | 138 | 106 | ||
| TORC2 controls endocytosis through plasma membrane tension | The Journal of Cell Biology | | 2019 | 627 | 194 | ||
| Sphingolipids and membrane targets for therapeutics | Current Opinion in Chemical Biology | | 2019 | 562 | 3 | ||
| Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity | Developmental cell | | 2019 | 260 | 217 | ||
| Target of rapamycin complex 2–dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae | The Journal of biological chemistry | | 2018 | 110 | 127 | ||
| Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2 | Nature Cell Biology | | 2018 | 613 | 2 | ||
| Regulation of Cellular Metabolism through Phase Separation of Enzymes | Biomolecules | | 2018 | 351 | 389 | ||
| Systematic analysis of complex genetic interactions | Science | | 2018 | 284 | 1,802 | ||
| Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2 | Nature Communications | | 2017 | 513 | 222 | ||
| TORC1 organized in inhibited domains (TOROIDs) regulate TORC1 activity | Nature | | 2017 | 508 | 0 | ||
| Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation | Journal of Biological Chemistry | | 2017 | 533 | 290 | ||
| A pathway of targeted autophagy is induced by DNA damage in budding yeast | Proceedings of the National Academy of Sciences | | 2017 | 505 | 289 | ||
| Tensing Up for Lipid Droplet Formation | Developmental Cell | | 2017 | 445 | 0 | ||
| TOR Complexes and the Maintenance of Cellular Homeostasis | Trends in Cell Biology | | 2016 | 525 | 0 | ||
| TORC2 Structure and Function | Trends in Biochemical Sciences | | 2016 | 573 | 2 | ||
| Dual action antifungal small molecule modulates multidrug efflux and TOR signaling | Nature chemical biology | | 2016 | 614 | 0 | ||
| A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction | Scientific Reports | | 2016 | 530 | 263 | ||
| TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae | Molecular Biology of the Cell | | 2016 | 496 | 259 | ||
| Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2 | Molecular Cell | | 2015 | 492 | 0 | ||
| Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways | Journal of Biological Chemistry | | 2015 | 496 | 273 | ||
| A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast | PLOS Genetics | | 2014 | 496 | 201 | ||
| Roles for PI(3,5)P2 in nutrient sensing through TORC1 | Molecular Biology of the Cell | | 2014 | 512 | 194 | ||
| Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis | Molecular Biology of the Cell | | 2014 | 562 | 345 | ||
| TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks | Molecular Cell | | 2013 | 468 | 0 | ||
| Growth control: function follows form | Current Biology | | 2013 | 460 | 247 | ||
| Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis | Nature cell biology | | 2012 | 1,075 | 2 | ||
| Amino acid signaling in high definition | Structure | | 2012 | 783 | 0 | ||
| Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry | ACS chemical biology | | 2012 | 645 | 1 | ||
| Chemical Biology Approaches to Membrane Homeostasis and Function | Chimia | | 2011 | 828 | 115 | ||
| Target of rapamycin (TOR) in nutrient signaling and growth control | Genetics | | 2011 | 668 | 3 | ||
| Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L | EMBO journal | | 2011 | 719 | 502 | ||
| Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae | Eukaryotic cell | | 2011 | 634 | 306 | ||
| A brief history of TOR | Biochemical Society transactions | | 2011 | 599 | 806 | ||
| Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast | Science signaling | | 2010 | 757 | 980 | ||
| Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology | Molecular biology of the cell | | 2009 | 749 | 662 | ||
| Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis | Genes & development | | 2009 | 712 | 841 | ||
| The Vam6 GEF controls TORC1 by activating the EGO complex | Molecular cell | | 2009 | 673 | 585 | ||
| Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling | Molecular cell | | 2009 | 667 | 504 | ||
| Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response | Molecular biology of the cell | | 2009 | 737 | 815 | ||
| Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 | PLoS biology | | 2009 | 760 | 889 | ||
| Caffeine extends yeast lifespan by targeting TORC1 | Molecular microbiology | | 2008 | 635 | 1,001 | ||
| Mutual antagonism of target of rapamycin and calcineurin signaling | The Journal of biological chemistry | | 2006 | 173 | 66 | ||
| The TOR signalling network from yeast to man | International journal of biochemistry & cell biology | | 2006 | 616 | 778 | ||
| TOR signaling in growth and metabolism | Cell | | 2006 | 1,003 | 1,818 | ||
| A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling | Cell | | 2006 | 681 | 1,181 | ||
| Cell growth control: little eukaryotes make big contributions | Oncogene | | 2006 | 682 | 2,642 |
