| Limited proteolysis-coupled mass spectrometry captures proteome-wide protein structural alterations and biomolecular condensation in living cells | Molecular systems biology |  | | 2026 | 14 | 94 |
|
| Structure and function of the yeast amino acid-sensing SEAC–EGOC supercomplex | Nature structural & molecular biology | | | 2026 | 15 | 124 |
|
| TOR signaling on membranes | FEBS letters |  | | 2025 | 13 | 0 |
|
| A dynamic feedback loop between retrograde sterol transport and TORC2 controls adaptation of the plasma membrane to stress | EMBO journal | | | 2025 | 24 | 38 |
|
| Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain | Nature | | | 2024 | 177 | 62 |
|
| Small Molecule Modulator of the mTORC2 Pathway Discovered from a DEL Library Designed to Bind to Pleckstrin Homology Domains | ACS chemical biology | | | 2024 | 36 | 68 |
|
| Dynamic metabolome profiling uncovers potential TOR signaling genes | eLife | | | 2023 | 221 | 261 |
|
| EGOC inhibits TOROID polymerization by structurally activating TORC1 | Nature structural & molecular biology | | | 2023 | 118 | 188 |
|
| Cryo-EM structure of the SEA complex | Nature | | | 2022 | 241 | 228 |
|
| Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast | Journal of cell science | | | 2022 | 182 | 634 |
|
| Passive coupling of membrane tension and cell volume during active response of cells to osmosis | Proceedings of the National Academy of Sciences of the United States of America | | | 2021 | 448 | 340 |
|
| Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides | ACS Central Science | | | 2021 | 367 | 710 |
|
| Flipper Probes for the Community | Chimia | | | 2021 | 476 | 357 |
|
| Chemical-Biology-derived in vivo Sensors: Past, Present, and Future | Chimia | | | 2021 | 159 | 314 |
|
| The flipside of the TOR coin – TORC2 and plasma membrane homeostasis at a glance | Journal of cell science | | | 2020 | 210 | 604 |
|
| TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast | The Journal of biological chemistry | | | 2020 | 243 | 239 |
|
| Phosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55 | Proteomics | | | 2020 | 185 | 0 |
|
| Resolving the Communication GAPs Upstream of TORC1 | Developmental cell | | | 2020 | 229 | 224 |
|
| Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9 | Molecular and Cellular Proteomics | | | 2020 | 495 | 294 |
|
| Structural Insights into TOR Signaling | Genes | | | 2020 | 436 | 123 |
|
| The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast | Molecular Cell | | | 2020 | 399 | 1 |
|
| TOR Signaling Is Going through a Phase | Cell metabolism | | | 2019 | 146 | 125 |
|
| TORC2 controls endocytosis through plasma membrane tension | The Journal of Cell Biology | | | 2019 | 635 | 209 |
|
| Sphingolipids and membrane targets for therapeutics | Current Opinion in Chemical Biology | | | 2019 | 570 | 3 |
|
| Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity | Developmental cell | | | 2019 | 268 | 244 |
|
| Target of rapamycin complex 2–dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae | The Journal of biological chemistry | | | 2018 | 118 | 141 |
|
| Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2 | Nature Cell Biology | | | 2018 | 621 | 2 |
|
| Regulation of Cellular Metabolism through Phase Separation of Enzymes | Biomolecules | | | 2018 | 362 | 456 |
|
| Systematic analysis of complex genetic interactions | Science | | | 2018 | 298 | 2,060 |
|
| Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2 | Nature Communications | | | 2017 | 520 | 230 |
|
| TORC1 organized in inhibited domains (TOROIDs) regulate TORC1 activity | Nature | | | 2017 | 515 | 0 |
|
| Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation | Journal of Biological Chemistry | | | 2017 | 540 | 331 |
|
| A pathway of targeted autophagy is induced by DNA damage in budding yeast | Proceedings of the National Academy of Sciences | | | 2017 | 513 | 329 |
|
| Tensing Up for Lipid Droplet Formation | Developmental Cell | | | 2017 | 452 | 0 |
|
| TOR Complexes and the Maintenance of Cellular Homeostasis | Trends in Cell Biology | | | 2016 | 533 | 0 |
|
| TORC2 Structure and Function | Trends in Biochemical Sciences | | | 2016 | 581 | 2 |
|
| Dual action antifungal small molecule modulates multidrug efflux and TOR signaling | Nature chemical biology | | | 2016 | 621 | 0 |
|
| A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction | Scientific Reports | | | 2016 | 537 | 286 |
|
| TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae | Molecular Biology of the Cell | | | 2016 | 504 | 272 |
|
| Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2 | Molecular Cell | | | 2015 | 500 | 0 |
|
| Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways | Journal of Biological Chemistry | | | 2015 | 503 | 333 |
|
| A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast | PLOS Genetics | | | 2014 | 503 | 218 |
|
| Roles for PI(3,5)P2 in nutrient sensing through TORC1 | Molecular Biology of the Cell | | | 2014 | 520 | 203 |
|
| Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis | Molecular Biology of the Cell | | | 2014 | 569 | 369 |
|
| TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks | Molecular Cell | | | 2013 | 477 | 0 |
|
| Growth control: function follows form | Current Biology | | | 2013 | 467 | 260 |
|
| Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis | Nature cell biology | | | 2012 | 1,085 | 2 |
|
| Amino acid signaling in high definition | Structure | | | 2012 | 794 | 0 |
|
| Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry | ACS chemical biology | | | 2012 | 654 | 1 |
|
| Chemical Biology Approaches to Membrane Homeostasis and Function | Chimia | | | 2011 | 837 | 135 |
|
| Target of rapamycin (TOR) in nutrient signaling and growth control | Genetics | | | 2011 | 678 | 3 |
|
| Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L | EMBO journal | | | 2011 | 729 | 524 |
|
| Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae | Eukaryotic cell | | | 2011 | 643 | 331 |
|
| A brief history of TOR | Biochemical Society transactions | | | 2011 | 608 | 843 |
|
| Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast | Science signaling | | | 2010 | 767 | 1,023 |
|
| Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology | Molecular biology of the cell | | | 2009 | 758 | 699 |
|
| Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis | Genes & development | | | 2009 | 721 | 883 |
|
| The Vam6 GEF controls TORC1 by activating the EGO complex | Molecular cell | | | 2009 | 683 | 646 |
|
| Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling | Molecular cell | | | 2009 | 676 | 526 |
|
| Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response | Molecular biology of the cell | | | 2009 | 747 | 840 |
|
| Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 | PLoS biology | | | 2009 | 769 | 1,242 |
|
| Caffeine extends yeast lifespan by targeting TORC1 | Molecular microbiology | | | 2008 | 645 | 1,085 |
|
| Mutual antagonism of target of rapamycin and calcineurin signaling | The Journal of biological chemistry | | | 2006 | 181 | 77 |
|
| The TOR signalling network from yeast to man | International journal of biochemistry & cell biology | | | 2006 | 625 | 847 |
|
| TOR signaling in growth and metabolism | Cell | | | 2006 | 1,013 | 1,909 |
|
| A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling | Cell | | | 2006 | 692 | 1,222 |
|
| Cell growth control: little eukaryotes make big contributions | Oncogene | | | 2006 | 692 | 2,786 |
|
