RL
Loewith, Robbie Joséph
Affiliation entities
Research groups
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain | Nature | 2024 | 9 | 6 | |||
Dynamic metabolome profiling uncovers potential TOR signaling genes | eLife | 2023 | 137 | 91 | |||
EGOC inhibits TOROID polymerization by structurally activating TORC1 | Nature structural & molecular biology | 2023 | 41 | 43 | |||
Cryo-EM structure of the SEA complex | Nature | 2022 | 162 | 47 | |||
Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast | Journal of cell science | 2022 | 116 | 111 | |||
Passive coupling of membrane tension and cell volume during active response of cells to osmosis | Proceedings of the National Academy of Sciences of the United States of America | 2021 | 341 | 96 | |||
Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides | ACS Central Science | 2021 | 292 | 137 | |||
Flipper Probes for the Community | Chimia | 2021 | 333 | 79 | |||
Chemical-Biology-derived in vivo Sensors: Past, Present, and Future | Chimia | 2021 | 89 | 66 | |||
The flipside of the TOR coin – TORC2 and plasma membrane homeostasis at a glance | Journal of cell science | 2020 | 159 | 134 | |||
TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast | The Journal of biological chemistry | 2020 | 152 | 58 | |||
Phosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55 | Proteomics | 2020 | 109 | 0 | |||
Resolving the Communication GAPs Upstream of TORC1 | Developmental cell | 2020 | 139 | 118 | |||
Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9 | Molecular and Cellular Proteomics | 2020 | 398 | 249 | |||
Structural Insights into TOR Signaling | Genes | 2020 | 373 | 52 | |||
The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast | Molecular Cell | 2020 | 338 | 1 | |||
TOR Signaling Is Going through a Phase | Cell metabolism | 2019 | 87 | 20 | |||
TORC2 controls endocytosis through plasma membrane tension | The Journal of Cell Biology | 2019 | 502 | 130 | |||
Sphingolipids and membrane targets for therapeutics | Current Opinion in Chemical Biology | 2019 | 466 | 3 | |||
Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity | Developmental cell | 2019 | 170 | 54 | |||
Target of rapamycin complex 2–dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae | The Journal of biological chemistry | 2018 | 50 | 55 | |||
Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2 | Nature Cell Biology | 2018 | 519 | 2 | |||
Regulation of Cellular Metabolism through Phase Separation of Enzymes | Biomolecules | 2018 | 297 | 183 | |||
Systematic analysis of complex genetic interactions | Science | 2018 | 151 | 179 | |||
Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2 | Nature Communications | 2017 | 432 | 195 | |||
TORC1 organized in inhibited domains (TOROIDs) regulate TORC1 activity | Nature | 2017 | 443 | 0 | |||
Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation | Journal of Biological Chemistry | 2017 | 432 | 166 | |||
A pathway of targeted autophagy is induced by DNA damage in budding yeast | Proceedings of the National Academy of Sciences | 2017 | 414 | 195 | |||
Tensing Up for Lipid Droplet Formation | Developmental Cell | 2017 | 373 | 0 | |||
TOR Complexes and the Maintenance of Cellular Homeostasis | Trends in Cell Biology | 2016 | 418 | 0 | |||
TORC2 Structure and Function | Trends in Biochemical Sciences | 2016 | 475 | 2 | |||
Dual action antifungal small molecule modulates multidrug efflux and TOR signaling | Nature chemical biology | 2016 | 532 | 0 | |||
A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction | Scientific Reports | 2016 | 454 | 169 | |||
TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae | Molecular Biology of the Cell | 2016 | 428 | 205 | |||
Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2 | Molecular Cell | 2015 | 430 | 0 | |||
Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways | Journal of Biological Chemistry | 2015 | 436 | 169 | |||
A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast | PLOS Genetics | 2014 | 424 | 128 | |||
Roles for PI(3,5)P2 in nutrient sensing through TORC1 | Molecular Biology of the Cell | 2014 | 437 | 148 | |||
Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis | Molecular Biology of the Cell | 2014 | 506 | 244 | |||
TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks | Molecular Cell | 2013 | 396 | 0 | |||
Growth control: function follows form | Current Biology | 2013 | 412 | 143 | |||
Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis | Nature cell biology | 2012 | 1 016 | 2 | |||
Amino acid signaling in high definition | Structure | 2012 | 740 | 0 | |||
Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry | ACS chemical biology | 2012 | 578 | 1 | |||
Chemical Biology Approaches to Membrane Homeostasis and Function | Chimia | 2011 | 696 | 55 | |||
Target of rapamycin (TOR) in nutrient signaling and growth control | Genetics | 2011 | 589 | 3 | |||
Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L | EMBO journal | 2011 | 646 | 445 | |||
Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae | Eukaryotic cell | 2011 | 593 | 274 | |||
A brief history of TOR | Biochemical Society transactions | 2011 | 533 | 640 | |||
Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast | Science signaling | 2010 | 672 | 719 | |||
Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology | Molecular biology of the cell | 2009 | 659 | 486 | |||
Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis | Genes & development | 2009 | 647 | 634 | |||
The Vam6 GEF controls TORC1 by activating the EGO complex | Molecular cell | 2009 | 591 | 432 | |||
Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling | Molecular cell | 2009 | 607 | 370 | |||
Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response | Molecular biology of the cell | 2009 | 649 | 724 | |||
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 | PLoS biology | 2009 | 664 | 474 | |||
Caffeine extends yeast lifespan by targeting TORC1 | Molecular microbiology | 2008 | 575 | 635 | |||
Mutual antagonism of target of rapamycin and calcineurin signaling | The Journal of biological chemistry | 2006 | 111 | 21 | |||
The TOR signalling network from yeast to man | International journal of biochemistry & cell biology | 2006 | 531 | 556 | |||
TOR signaling in growth and metabolism | Cell | 2006 | 819 | 1 258 | |||
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling | Cell | 2006 | 608 | 1 048 | |||
Cell growth control: little eukaryotes make big contributions | Oncogene | 2006 | 588 | 2 356 |