RL
Loewith, Robbie Joséph
| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| Limited proteolysis-coupled mass spectrometry captures proteome-wide protein structural alterations and biomolecular condensation in living cells | Molecular systems biology |  | 2026 | 1 | 0 | ||
| Structure and function of the yeast amino acid-sensing SEAC–EGOC supercomplex | Nature structural & molecular biology | | 2026 | 1 | 0 | ||
| TOR signaling on membranes | FEBS letters |  | 2025 | 1 | 0 | ||
| A dynamic feedback loop between retrograde sterol transport and TORC2 controls adaptation of the plasma membrane to stress | EMBO journal | | 2025 | 7 | 6 | ||
| Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain | Nature | | 2024 | 162 | 38 | ||
| Small Molecule Modulator of the mTORC2 Pathway Discovered from a DEL Library Designed to Bind to Pleckstrin Homology Domains | ACS chemical biology | | 2024 | 24 | 36 | ||
| Dynamic metabolome profiling uncovers potential TOR signaling genes | eLife | | 2023 | 211 | 168 | ||
| EGOC inhibits TOROID polymerization by structurally activating TORC1 | Nature structural & molecular biology | | 2023 | 106 | 132 | ||
| Cryo-EM structure of the SEA complex | Nature | | 2022 | 231 | 90 | ||
| Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast | Journal of cell science | | 2022 | 173 | 326 | ||
| Passive coupling of membrane tension and cell volume during active response of cells to osmosis | Proceedings of the National Academy of Sciences of the United States of America | | 2021 | 434 | 247 | ||
| Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides | ACS Central Science | | 2021 | 354 | 270 | ||
| Flipper Probes for the Community | Chimia | | 2021 | 463 | 225 | ||
| Chemical-Biology-derived in vivo Sensors: Past, Present, and Future | Chimia | | 2021 | 150 | 165 | ||
| The flipside of the TOR coin – TORC2 and plasma membrane homeostasis at a glance | Journal of cell science | | 2020 | 199 | 388 | ||
| TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast | The Journal of biological chemistry | | 2020 | 232 | 124 | ||
| Phosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55 | Proteomics | | 2020 | 172 | 0 | ||
| Resolving the Communication GAPs Upstream of TORC1 | Developmental cell | | 2020 | 216 | 183 | ||
| Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9 | Molecular and Cellular Proteomics | | 2020 | 482 | 274 | ||
| Structural Insights into TOR Signaling | Genes | | 2020 | 425 | 81 | ||
| The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast | Molecular Cell | | 2020 | 386 | 1 | ||
| TOR Signaling Is Going through a Phase | Cell metabolism | | 2019 | 134 | 68 | ||
| TORC2 controls endocytosis through plasma membrane tension | The Journal of Cell Biology | | 2019 | 623 | 174 | ||
| Sphingolipids and membrane targets for therapeutics | Current Opinion in Chemical Biology | | 2019 | 556 | 3 | ||
| Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity | Developmental cell | | 2019 | 256 | 169 | ||
| Target of rapamycin complex 2–dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae | The Journal of biological chemistry | | 2018 | 108 | 109 | ||
| Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2 | Nature Cell Biology | | 2018 | 607 | 2 | ||
| Regulation of Cellular Metabolism through Phase Separation of Enzymes | Biomolecules | | 2018 | 344 | 320 | ||
| Systematic analysis of complex genetic interactions | Science | | 2018 | 281 | 943 | ||
| Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2 | Nature Communications | | 2017 | 510 | 218 | ||
| TORC1 organized in inhibited domains (TOROIDs) regulate TORC1 activity | Nature | | 2017 | 505 | 0 | ||
| Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation | Journal of Biological Chemistry | | 2017 | 527 | 238 | ||
| A pathway of targeted autophagy is induced by DNA damage in budding yeast | Proceedings of the National Academy of Sciences | | 2017 | 502 | 266 | ||
| Tensing Up for Lipid Droplet Formation | Developmental Cell | | 2017 | 441 | 0 | ||
| TOR Complexes and the Maintenance of Cellular Homeostasis | Trends in Cell Biology | | 2016 | 523 | 0 | ||
| TORC2 Structure and Function | Trends in Biochemical Sciences | | 2016 | 571 | 2 | ||
| Dual action antifungal small molecule modulates multidrug efflux and TOR signaling | Nature chemical biology | | 2016 | 610 | 0 | ||
| A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction | Scientific Reports | | 2016 | 524 | 231 | ||
| TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae | Molecular Biology of the Cell | | 2016 | 492 | 232 | ||
| Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2 | Molecular Cell | | 2015 | 490 | 0 | ||
| Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways | Journal of Biological Chemistry | | 2015 | 493 | 212 | ||
| A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast | PLOS Genetics | | 2014 | 493 | 167 | ||
| Roles for PI(3,5)P2 in nutrient sensing through TORC1 | Molecular Biology of the Cell | | 2014 | 508 | 178 | ||
| Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis | Molecular Biology of the Cell | | 2014 | 560 | 312 | ||
| TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks | Molecular Cell | | 2013 | 466 | 0 | ||
| Growth control: function follows form | Current Biology | | 2013 | 455 | 182 | ||
| Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis | Nature cell biology | | 2012 | 1,071 | 2 | ||
| Amino acid signaling in high definition | Structure | | 2012 | 777 | 0 | ||
| Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry | ACS chemical biology | | 2012 | 641 | 1 | ||
| Chemical Biology Approaches to Membrane Homeostasis and Function | Chimia | | 2011 | 818 | 88 | ||
| Target of rapamycin (TOR) in nutrient signaling and growth control | Genetics | | 2011 | 663 | 3 | ||
| Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L | EMBO journal | | 2011 | 715 | 485 | ||
| Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae | Eukaryotic cell | | 2011 | 631 | 293 | ||
| A brief history of TOR | Biochemical Society transactions | | 2011 | 596 | 750 | ||
| Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast | Science signaling | | 2010 | 752 | 896 | ||
| Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology | Molecular biology of the cell | | 2009 | 743 | 587 | ||
| Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis | Genes & development | | 2009 | 706 | 784 | ||
| The Vam6 GEF controls TORC1 by activating the EGO complex | Molecular cell | | 2009 | 667 | 514 | ||
| Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling | Molecular cell | | 2009 | 662 | 452 | ||
| Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response | Molecular biology of the cell | | 2009 | 731 | 778 | ||
| Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 | PLoS biology | | 2009 | 753 | 611 | ||
| Caffeine extends yeast lifespan by targeting TORC1 | Molecular microbiology | | 2008 | 629 | 868 | ||
| Mutual antagonism of target of rapamycin and calcineurin signaling | The Journal of biological chemistry | | 2006 | 171 | 54 | ||
| The TOR signalling network from yeast to man | International journal of biochemistry & cell biology | | 2006 | 610 | 683 | ||
| TOR signaling in growth and metabolism | Cell | | 2006 | 998 | 1,683 | ||
| A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling | Cell | | 2006 | 677 | 1,133 | ||
| Cell growth control: little eukaryotes make big contributions | Oncogene | | 2006 | 677 | 2,542 |
