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Scientific article
English

Effect of Ketamine on Rumination in Treatment-Resistant Depressive Patients

Published inJournal of Clinical Psychopharmacology, vol. 40, no. 6, p. 607-610
Publication date2020
Abstract

A rapid antidepressant effect of ketamine has repeatedly been documented in the literature, and identifying clinical features associated with a better response to this treatment is currently an essential question. Considering the relationship between rumination and depression and the need to identify potential predictors of response to ketamine, we analyzed the effect of a single injection of ketamine 0.5 mg/kg on rumination in treatment-resistant depressive (TRD) patients and explored whether baseline ruminative style and early improvements of rumination would predict a greater antidepressant effect of ketamine.

Keywords
  • Ketamine
  • Rumination
  • Major depressive disorder
  • Treatment resistant
  • Bolus
Funding
  • Swiss National Science Foundation - 135554
Citation (ISO format)
VIDAL, Sonia et al. Effect of Ketamine on Rumination in Treatment-Resistant Depressive Patients. In: Journal of Clinical Psychopharmacology, 2020, vol. 40, n° 6, p. 607–610. doi: 10.1097/JCP.0000000000001305
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Article (Published version)
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Identifiers
ISSN of the journal0271-0749
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Technical informations

Creation10/27/2020 4:49:00 PM
First validation10/27/2020 4:49:00 PM
Update time03/16/2023 12:04:49 AM
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