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Title

Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity

Authors
Bertsias, George K
Gergianaki, Irini
Tektonidou, Maria G
Trachana, Maria
Bielser, Deborah
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Published in Annals of the Rheumatic Diseases. 2019, vol. 78, no. 8, p. 1079-1089
Abstract Systemic lupus erythematosus (SLE) diagnosis and treatment remain empirical and the molecular basis for its heterogeneity elusive. We explored the genomic basis for disease susceptibility and severity.
Keywords AdultCase-Control StudiesDisease ProgressionFemaleGene Expression Profiling/methodsGenetic Predisposition to Disease/epidemiologyGenetic VariationGenome-Wide Association StudyGenotypeHumansInterferon Type I/geneticsLupus ErythematosusSystemic/genetics/immunologyMaleMiddle AgedPhenotypeRNAMessenger/geneticsReference ValuesTranscriptome/geneticsYoung Adult
Identifiers
PMID: 31167757
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Research group Population Genomics and Genetics of Complex Traits (892)
Projects
FNS: 31003A-170096
H2020: LUPUSCARE
H2020: SYSCID
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(ISO format)
PANOUSIS, Nikolaos et al. Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity. In: Annals of the Rheumatic Diseases, 2019, vol. 78, n° 8, p. 1079-1089. doi: 10.1136/annrheumdis-2018-214379 https://archive-ouverte.unige.ch/unige:144675

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Deposited on : 2020-11-13

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