Associations between age-related changes in bone microstructure and strength and dietary acid load in a cohort of community-dwelling, healthy men and postmenopausal women

Papageorgiou, Maria; Merminod, Fanny; Chevalley, Thierry; van Rietbergen, Bert; Ferrari, Serge Livio; Rizzoli, René; Biver, Emmanuel

doi:10.1093/ajcn/nqaa191

Scientific article

English

Associations between age-related changes in bone microstructure and strength and dietary acid load in a cohort of community-dwelling, healthy men and postmenopausal women

ContributorsPapageorgiou, Maria; Merminod, Fanny; Chevalley, Thierry

; van Rietbergen, Bert; Ferrari, Serge Livio; Rizzoli, René; Biver, Emmanuel

Published inThe American Journal of Clinical Nutrition, vol. 112, no. 4, p. 1120-1131

Publication date2020

Abstract

Background: The importance of dietary acid load (DAL) in the pathogenesis of osteoporosis is still debated. Age-related changes in bone microstructure and strength in relation to DAL remain largely unexplored. Objectives: We investigated the associations between changes in areal and volumetric bone mineral density (BMD), bone microstructure and strength, fracture risk, and DAL in a prospective cohort of 65-y-old healthy men and postmenopausal women.

Keywords

Acid-ash theory
Bone microstructure
Bone mineral density
Bone strength
Dietary acid load
Fractures
Osteoporosis

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Génétique des ostéoporoses (544)

Citation (ISO format)

PAPAGEORGIOU, Maria et al. Associations between age-related changes in bone microstructure and strength and dietary acid load in a cohort of community-dwelling, healthy men and postmenopausal women. In: The American Journal of Clinical Nutrition, 2020, vol. 112, n° 4, p. 1120–1131. doi: 10.1093/ajcn/nqaa191

Article (Published version)

Supplemental data

Identifiers

PID : unige:144116
DOI : 10.1093/ajcn/nqaa191
PMID : 32678420

Additional URL for this publicationhttps://academic.oup.com/ajcn/article/112/4/1120/5873028

Journal ISSN0002-9165

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Creation06/10/2020 11:02:00

First validation06/10/2020 11:02:00

Update15/03/2023 22:56:50

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Associations between age-related changes in bone microstructure and strength and dietary acid load in a cohort of community-dwelling, healthy men and postmenopausal women

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