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Atteintes de la sphère ORL et cervicofaciale dans la maladie à IgG4

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Published in Revue médicale suisse. 2020, vol. 16, no. 709, p. 1870-1875
Abstract IgG4-related disease is a rare multi-organic inflammatory disease that frequently involves the ENT and head and neck areas. In these cases, salivary gland and lacrimal gland involvement is very common and includes enlargement, infiltration, and formation of pseudotumours. Diagnosis of IgG4 related disease remains a challenge and relies on several clinical, serological, radiological and histopathological criteria to differentiate from other diseases with similar clinical presentation. Histology reveals IgG4 positive lymphoplasmocytic infiltrates, storiform fibrosis and obliterative phlebitis. Glucocorticoids are the first line of treatment and can be combined with other immunosuppressants. The prognosis is favorable if treatment is initiated early. Recurrences are common. Delay in diagnosis can have severe multi-organic consequences.
PMID: 33026730
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Research groups Groupe Becker Minerva (imagerie ORL) (683)
Laboratoire d'immunologie translationnelle (856)
Neuroprothèses sensorielles pour la restitution de l'audition et l'équilibre (268)
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LIARD, Yannick et al. Atteintes de la sphère ORL et cervicofaciale dans la maladie à IgG4. In: Revue médicale suisse, 2020, vol. 16, n° 709, p. 1870-1875. https://archive-ouverte.unige.ch/unige:143424

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Deposited on : 2020-10-22

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