Scientific article
Open access

SiR–Hoechst is a far-red DNA stain for live-cell nanoscopy

Published inNature Communications, vol. 6, no. 1
Publication date2015

Cell-permeable DNA stains are popular markers in live-cell imaging. Currently used DNA stains for live-cell imaging are either toxic, require illumination with blue light or are not compatible with super-resolution microscopy, thereby limiting their utility. Here we describe a far-red DNA stain, SiR–Hoechst, which displays minimal toxicity, is applicable in different cell types and tissues, and is compatible with super-resolution microscopy. The combination of these properties makes this probe a powerful tool for live-cell imaging.

Citation (ISO format)
LUKINAVIČIUS, Gražvydas et al. SiR–Hoechst is a far-red DNA stain for live-cell nanoscopy. In: Nature Communications, 2015, vol. 6, n° 1. doi: 10.1038/ncomms9497
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Article (Published version)
ISSN of the journal2041-1723

Technical informations

Creation10/08/2020 3:35:00 PM
First validation10/08/2020 3:35:00 PM
Update time03/15/2023 10:48:33 PM
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