SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans
Contributeurs/tricesChae, Heeyoung; Augustin, Robert; Gatineau, Eva; Mayoux, Eric; Bensellam, Mohammed; Antoine, Nancy; Khattab, Firas; Lai, Bao-Khanh; Brusa, Davide; Stierstorfer, Birgit; Klein, Holger; Singh, Bilal; Ruiz, Lucie; Pieper, Michael; Mark, Michael; Herrera, Pedro Luis; Gribble, Fiona M.; Reimann, Frank; Wojtusciszyn, Anne; Broca, Christophe; Rita, Nano; Piemonti, Lorenzo; Gilon, Patrick
Publié dansMolecular Metabolism, 101071
Date de publication2020
Résumé
Mots-clés
- No direct effect of SGLT2i on α- and β-cells
- Gliflozins
- SGLT2 inhibitor
- Glucagon
- Insulin
- Diabetes
Structure d'affiliation
Groupe de recherche
Citation (format ISO)
CHAE, Heeyoung et al. SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans. In: Molecular Metabolism, 2020, p. 101071. doi: 10.1016/j.molmet.2020.101071
Fichiers principaux (1)
Article (Accepted version)
Identifiants
- PID : unige:141161
- DOI : 10.1016/j.molmet.2020.101071
- PMID : 32896668
ISSN du journal2212-8778